2018
DOI: 10.1101/425074
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Laparoscopic Roux-en-Y gastric bypass profoundly changes gut microbiota compared to laparoscopic sleeve gastrectomy: a metagenomic comparative analysis

Abstract: Affiliations 1. ENTEROME, 94/96 av. Ledru Rollin, Abstract Background: Bariatric surgery is an effective therapeutic procedure for morbidly obese patients as it induces sustained weight loss. The two most common interventions are Laparoscopic Sleeve Gastrectomy (LSG) and Laparoscopic Roux-en-Y Gastric Bypass (LRYGB). Objective: Characterizing the gut microbiota changes induced by LSG and LRYGB. Design: 89 and 108 patients who underwent LSG and LRYGB respectively, were recruited from three countries: USA, Franc… Show more

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“…The composition of the gut microbiota shifts promptly in humans as soon as 1-3 months after surgery 4,5,10 , and those changes have been reported to persist 12 months post-surgery 5,7,10,12 . Additionally, a number of studies 4,5,7,10,11,[13][14][15] have evaluated the fecal microbiota after RYGB in longitudinal cohorts.…”
Section: Introductionmentioning
confidence: 99%
“…The composition of the gut microbiota shifts promptly in humans as soon as 1-3 months after surgery 4,5,10 , and those changes have been reported to persist 12 months post-surgery 5,7,10,12 . Additionally, a number of studies 4,5,7,10,11,[13][14][15] have evaluated the fecal microbiota after RYGB in longitudinal cohorts.…”
Section: Introductionmentioning
confidence: 99%