Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity: case-control study

Chouillard, Élie; Karaa, Aziz; Elkhoury, Mansour; Greco, Vincenzo J.

doi:10.1016/j.soard.2011.01.037

Cited by 74 publications

(24 citation statements)

References 26 publications

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“…That may become higher than 90% in diabetes mellitus or obstructive sleep apnea and more than 50% in hypertension. There are few data in the literature [19, 28, 29] comparing results between LRYGB and LSG, but the present data show similar resolution rate with both surgical techniques.…”

Section: Discussionsupporting

confidence: 38%

Short- and Midterm Results between Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy for the Treatment of Morbid Obesity

2013

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Background. Laparoscopic Roux-en-Y gastric bypass (LRYGB) is one of the most widely used bariatric procedures today, and laparoscopic sleeve gastrectomy (LSG) as a single-stage procedure for the treatment of morbid obesity is becoming increasingly popular in Europe. The aim of this study was to compare short- and midterm results between LRYGB and LSG. Methods. An observational retrospective study from a database of patients undergoing LRYGB and LSG between January 2008 and June 2011. Seventy patients (mean age 39 years) were included. Patients were followed at 6, 12, and 18 months. Operative time, length of stay, weight loss, comorbidity improvement or resolution, postoperative complications, reinterventions and mortality were evaluated. Results. Thirty-six LRYGB and 34 LSG were included. Mean operative time of LSG was 106 min while LRYGB was 196 min (P < 0.001). Differences in length of stay, early and late complications, and improvement or resolution in comorbidities were not significant (P > 0.05). Eighteen months after surgery, average excess weight loss was 77.6% in LRYGB and 57.1% in LSG (P = 0.003). There was no surgery-related mortality. Conclusions. Both LRYGB and LSG are safe procedures that provide good results in weight loss and resolution of comorbidities at 18 months.

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Section: Discussionsupporting

confidence: 38%

Short- and Midterm Results between Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy for the Treatment of Morbid Obesity

2013

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“…23 Data from a meta-analysis of 27 studies that evaluated medical outcomes after LSG found that diabetes resolved in 66% of patients. 24 The results from most, 18,19,22,25–27 but not all, 20,28,29 studies that compared LSG with other therapeutic interventions found T2D remission rates after LSG were the same as those achieved after RYGB surgery, 18,19,22,25–27 but greater than those achieved after conventional medical therapy, 30,31 or LAGB. 27,32 The clinical improvement in T2D after bariatric surgery results in full recovery of the cost of surgery within a few years, primarily because of the decreased need for medications used to treat diabetes and its associated complications.…”

Section: Effect Of Bariatric Surgery On Type 2 Diabetesmentioning

confidence: 99%

Effects of Bariatric Surgery on Glucose Homeostasis and Type 2 Diabetes

2012

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Obesity is an important risk factor for type 2 diabetes (T2D). Weight loss improves the major factors involved in the pathogenesis of T2D, namely insulin action and β-cell function, and is considered a primary therapy for obese patients who have T2D. Unfortunately, most patients with T2D fail to achieve successful weight loss and adequate glycemic control from medical therapy. In contrast, bariatric surgery causes marked weight loss and complete remission of T2D in most patients. Moreover, bariatric surgical procedures that divert nutrients away from the upper gastrointestinal tract are more successful in producing weight loss and remission of T2D than those that simply restrict stomach capacity. Although upper gastrointestinal tract bypass procedures alter the metabolic response to meal ingestion, by increasing early post-prandial plasma concentrations of glucagon-like peptide 1 and insulin, it is not clear whether these effects make an important contribution to long-term control of glycemia and T2D once substantial surgery-induced weight loss has occurred. Nonetheless, the effects of surgery on body weight and metabolic function indicate that bariatric surgery should be part of the standard therapy for T2D. More research is needed to advance our understanding of the physiological effects of different bariatric surgical procedures and possible weight loss-independent factors that improve metabolic function and contribute to the resolution of T2D.

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“…Others have had to resort to surgical treatment for this condition, and the treatment options include revision sleeve gastrectomy, seromyotomy and Roux-en-Y gastric bypass [8,10]. The adverse event rates for these surgical procedures seem to be very high, and the success rates are not encouraging [11]. Two recent studies [12,13] report the use of pneumatic achalasia balloon dilators in a small number of patients.…”

Section: Introductionmentioning

confidence: 99%

Evolving Endoscopic Management Options for Symptomatic Stenosis Post-Laparoscopic Sleeve Gastrectomy for Morbid Obesity: Experience at a Large Bariatric Surgery Unit in New Zealand

Ogra

Kini

2014

OBES SURG

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Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity: case-control study

Cited by 74 publications

References 26 publications

Short- and Midterm Results between Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy for the Treatment of Morbid Obesity

Short- and Midterm Results between Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy for the Treatment of Morbid Obesity

Effects of Bariatric Surgery on Glucose Homeostasis and Type 2 Diabetes

Evolving Endoscopic Management Options for Symptomatic Stenosis Post-Laparoscopic Sleeve Gastrectomy for Morbid Obesity: Experience at a Large Bariatric Surgery Unit in New Zealand

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