Laparoscopic splenectomy for sclerosing angiomatoid nodular transformation of the spleen

Abstract

Sclerosing angiomatoid nodular transformation (SANT) is a rare, benign, proliferative vascular lesion that arises from the splenic red pulp. Most patients with SANT have no clinical symptoms and are discovered incidentally on imaging. There are no definitive radiological signs and a distinction from other splenic diseases, and malignant processes remain difficult. Confirmation of the diagnosis of SANT requires a histological and immunohistochemical evaluation of the resected spleen. Here, we report an unusual case of SANT of the spleen successfully treated with an elective laparoscopic splenectomy (LS). LS is a safe and effective method for diagnosis of SANT.

Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review

“…SANT of the spleen is a benign disease that does not require surgery unless the patient is symptomatic. However, due to diagnostic dilemma, most patients undergo splenectomy to rule out malignancy or another pathological disease of the spleen[ 9 ]. In our case, the patient underwent laparoscopic splenectomy and recovered without complications.…”

Sclerosing angiomatoid nodular transformation presenting with thrombocytopenia after laparoscopic splenectomy - Case report and systematic review of 230 patients

“…The curative treatment for SANT is splenectomy [ 46 , [48] , [49] , [50] , [51] , [52] , [53] , [55] , [56] , [57] , [58] , [59] , [60] ]. Open splenectomy or minimally invasive splenectomy are both options for surgical treatment [ [62] , [63] , [64] , [65] , [66] , [67] , [68] , [70] , [71] , [72] , [73] , [74] , [75] , [76] , [77] ]. In recent years, minimally invasive surgery such as robotic or laparoscopic splenectomy has become more popular due to a shorter hospital stay, less postoperative abdominal pain, and an early return to normal activity [ 18 , [63] , [64] , [65] , 78 ].…”

“…Open splenectomy or minimally invasive splenectomy are both options for surgical treatment [ [62] , [63] , [64] , [65] , [66] , [67] , [68] , [70] , [71] , [72] , [73] , [74] , [75] , [76] , [77] ]. In recent years, minimally invasive surgery such as robotic or laparoscopic splenectomy has become more popular due to a shorter hospital stay, less postoperative abdominal pain, and an early return to normal activity [ 18 , [63] , [64] , [65] , 78 ]. After total splenectomy, no evidence of recurrence was reported in the follow-up period (median follow-up:12 months (0–166)).…”

Sclerosing angiomatoid nodular transformation (SANT) of spleen mimicking a splenic abscess: Case report and review of the literature

“…However, these procedure carries risks of bleeding and needle tract seeding [20]. Therefore, splenectomy may be the preferred modality to rule out malignancy or other pathological processes [24]. In addition the review of Cao et al showed that patients with SANT, indeed, have a relatively high prevalence of coexistence with diseases at other organs [17,18].…”