Laparoscopic splenectomy for splenic masses

Abstract

Laparoscopic splenectomy is appropriate for patients whose indication for surgery is splenic mass. Suspicious splenic masses should be removed due to the relatively high incidence of malignant pathology, most commonly lymphoma.

Adverse postoperative outcomes in surgical patients with immune thrombocytopenia

“…The leading causes of death included bleeding, infection, complications from therapies and others unrelated to ITP itself, , . Studies exploring surgical mortality rates in patients with ITP focused mainly on splenectomy, and reported mortality rates below 1·0 per cent on average, no higher than in non‐ITP controls. Investigations in procedures other than splenectomy are extremely rare, with equivocal findings, .…”

Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura: results of a prospective multicenter phase 2 study

“…[11][12][13] Moreover, some authors reported that, despite initial good responses to splenectomy, the risk of late relapse persists during long-term follow-up 14,15 and severe morbidity resulting from surgery is associated with 11% to 30% postoperative complications requiring prolonged hospitalization or readmission. 11,16 For these reasons, an effective and safe alternative to splenectomy would improve management of chronic ITP.…”

“…11-13 Moreover, some authors reported that, despite initial good responses to splenectomy, the risk of late relapse persists during long-term follow-up 14,15 and severe morbidity resulting from surgery is associated with 11% to 30% postoperative complications requiring prolonged hospitalization or readmission. 11,16 For these reasons, an effective and safe alternative to splenectomy would improve management of chronic ITP.Rituximab is a chimeric, humanized monoclonal antibody directed against the CD20 determinant on B cells. It was initially developed for the treatment of malignant lymphoma but has also been used in autoantibody-mediated disorders, such as rheumatoid arthritis, 17 systemic lupus erythematosus, 18 autoimmune hemolytic anemia, 19 or thrombotic thrombocytopenic purpura.…”

Linfangioma esplênico: um raro tumor benigno do baço tratado por cirurgia laparoscópica

“…Routine laboratory tests and simple chest and abdominal X-rays generally show no abnormalities6. The differential diagnosis is extensive and includes lymphoma (a more common malignant tumor), infarction, septic embolism, metastases (melanoma, breast, ovarian and lung cancer), and splenic cysts 11 . In the present case, the patient was symptomatic and a mass was palpable in the abdomen.…”