Laparoscopic versus open distal gastrectomy for early gastric cancer in Japan: long-term clinical outcomes of a randomized clinical trial

Abstract

LADG was associated with less wound pain during long-term follow-up after surgery, whereas symptoms related to overeating were common. Based on our findings and the patients' reported satisfaction, we recommend LADG for cT1 gastric cancer as an effective procedure with excellent long-term survival.

Laparoscopic‐assisted versus open radical gastrectomy for resectable gastric cancer: Systematic review, meta‐analysis, and trial sequential analysis of randomized controlled trials

“…Also, we checked the references of relevant reviews, published meta‐analyses and possible included studies. Finally, 14 RCTs totaling 2,307 gastric cancer survivors (1,163 laparoscopic and 1,144 open) were included in present meta‐analysis .…”

“…Laparoscopic‐assisted gastrectomy (LAG) with minimal invasiveness acquired huge popularity in the past two decades , since the first case was performed and reported by Kitano et al in 1991 . Many clinical trials were commenced to evaluate possible advantage and underlying risk associated with LAG and subsequent meta‐analyses have suggested the potential short‐term superiority of LAG over OG in reducing intraoperative blood loss and hospital stay, and accelerating postoperative flatus .…”

“…Now, new evidence from longer follow‐up RCTs with inconsistent results was reported . Therefore, an updated meta‐analysis of randomized controlled trials was conducted to compare the safety and efficacy of LAG with OG for resectable gastric cancer, including relevant data on hospital costs, patient satisfaction and quality of life.…”

Learning curve for gastric cancer patients with laparoscopy-assisted distal gastrectomy

“…[7,8] The benefits of LADG, such as better visualization, less-estimated blood loss, [9] lower complication rate, [9,10] shorter length of hospital stays, [10,11] and better survival outcomes [1,6] have been well documented. In addition to being safe and technically feasible, LADG has been demonstrated in several studies to yield acceptable oncologic outcomes, not only for early GC patients, [3,9,10,12] but also for those who were with advanced GC. [4–6,11,13,14] …”

Local resection of the stomach for gastric cancer

“…Surgery, in most of these cases involves laparoscopic gastrectomy [30] with lymph node dissection up to ‘D1+’. Among these cases of surgical resections, only 20 % have lymph node metastasis.…”