“…Key words: Hepatocellular carcinoma -Liver cirrhosis -Laparoscopic ultrasound -Radiofrequency interstitial thermal ablation In recent years, laparoscopy with laparoscopic ultrasound (L-LUS) introduced the option of a fairly aggressive and accurate staging modality in the pretreatment evaluation of cirrhotic patients with hepatocellular carcinoma (HCC) [11, 28,39]. Furthermore, L-LUS allows the performance of US-guided biopsy [36] or interstitial therapies, such as ethanol injection, cryoablation, or radiofrequency interstitial thermal ablation (RITA), in the same session [8,15,16,22,31].…”