Laparoscopic vs open resection of pancreatic endocrine neoplasms: single institution’s experience over 14 years

Gumbs, Andrew A.; Grès, Philippe; Madureira, Fábio Athayde Veloso; Gayet, Brice

doi:10.1007/s00423-007-0255-5

Cited by 25 publications

(18 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pancreatic fistula is the most frequent complication of distal pancreatectomy regardless of the approach 14,17,19,21,26 . The frequency of pancreatic fistula in this study (38%) is similar to the literature 10,16,17 . Several techniques and pitfalls have been proposed to reduce this complication, such as suture reinforcement 20 , individual ligation of Wirsung´s duct 20 , different types mechanical staples loads 22 , coating of suture lines with absorbable material 25 , and very slow closure of the stapler 18 .…”

Section: Summarizes the Expected Results Of The Cyst´s Fluid Analysissupporting

confidence: 79%

See 1 more Smart Citation

Ressecção laparoscópica dos cistoadenomas pancreáticos

Farah

Lupinacci

Apodaca-Torres

2012

ABCD, arq. bras. cir. dig.

View full text Add to dashboard Cite

-Background -Laparoscopic pancreatic resections have become increasingly frequent with good results reported by several centers. However, few studies have focused on laparoscopic treatment of pancreatic cystic lesions. Aim -To analyze the results of minimally invasive treatment of pancreatic cystic lesions. Methods -Were included all laparoscopic pancreatic resections performed at three centers. Surgical procedures included resection of the pancreas and left enucleations (with or without splenectomy). The post-operative complications were classified according to the classification proposed by Clavien and Dindo6. The diagnosis of pancreatic fistula was confirmed if the amylase dosage of the drainage liquid in the third postoperative day was more than three times the amount of serum amylase. Results -Were performed 44 laparoscopic pancreatic resections. Fifteen patients underwent surgery for suspected pancreatic cystadenoma and 13 had this diagnosis confirmed. There were 12 women (92%), and the average age of patients was 50 years. Six patients had minor postoperative complications. There were five (38%) pancreatic fistulas, neither considered as severe (C), and only one patient required hospital readmission and radiological drainage. In this series, there were no conversions, reoperations, or mortality. Conclusions -The laparoscopic approach is a safe and effective option for the treatment of pancreatic cystic lesions. The incidence of pancreatic fistula has good evolution and not diminishes the benefits of minimally invasive surgery. ABCDDV/866RESUMO -Racional -As ressecções pancreáticas por laparoscopia tem se tornado cada vez mais frequentes, com bons resultados relatados por vários centros. Entretanto, poucos estudos se concentraram no tratamento laparoscópico das lesões císticas pancreáticas. Objetivo -Analisar os resultados do tratamento minimamente invasivo das lesões císticas pancreáticas. Métodos -Análise retrospectiva de um banco de dados prospectivo multicêntrico brasileiro. Foram incluídas todas as ressecções pancreáticas laparoscópicas realizadas em três centros. Os procedimentos cirúrgicos incluíram enucleações e ressecções do pâncreas esquerdo (com ou sem esplenectomia associada). As complicações pos-operatórias foram classificadas de acordo com a classificação proposta por Clavien e Dindo6. O diagnóstico de fístula pancreática foi confirmado se a dosagem de amilase do líquido de drenagem no 3o dia pós-operatório era superior a três vezes o valor da amilase sérica. Resultados -Foram realizadas 44 ressecções pancreáticas por laparoscopia. Quinze pacientes foram operados com suspeita de cistoadenoma pancreático e 13 tiveram o diagnóstico confirmado. Foram operadas 12 mulheres (92%), e a idade média foi de 50 anos. Seis pacientes tiveram complicações pós-operatórias leves. Ocorreram cinco (38%) fístulas pancreáticas, nenhuma considerada grave (C) e apenas um paciente necessitou re-internação hospitalar e drenagem radiológica. Nesta série não houve conversões, re-operações ou mortalidade. Conc...

show abstract

Section: Summarizes the Expected Results Of The Cyst´s Fluid Analysissupporting

confidence: 79%

“…Laparoscopic pancreatic resections have become increasingly frequent, with excellent results reported by several centers 7,10,19,26 . However, few studies have focused on laparoscopic treatment of pancreatic cystic lesions.…”

Section: Introductionmentioning

confidence: 99%

Ressecção laparoscópica dos cistoadenomas pancreáticos

Farah

Lupinacci

Apodaca-Torres

2012

ABCD, arq. bras. cir. dig.

View full text Add to dashboard Cite

show abstract

“…In our series, no local recurrence from malignant tumor was reported, including the only patient with infiltrated margins at histology, where severe pancreatitis and the synchronous presence of liver and lymph node metastasis prevented us from performing any further, more radical surgery. Based on our experience in laparoscopic and open pancreatic enucleation [16, 17, 33], we believe that a thorough preoperative work-up and intraoperative US may allow for laparoscopic enucleation/atypical resection of malignant/ uncertain tumors in selected patients, as confirmed by others [4, 5, 8, 13]. The exiguous number of patients with malignant disease treated by enucleation so far clearly does not allow for any definitive conclusions.…”

Section: Discussionmentioning

confidence: 91%

“…With the purpose of evaluating the results of laparoscopic pancreatic minor surgery, here we present the short- and long-term results (5-year mean follow-up) of a monocentric series of 33 patients undergoing laparoscopic pancreatic enucleation/atypical resection over a 15-year period in a center specializing in the laparoscopic approach to abdominal solid organs [14, 15], including pancreatic surgery [16, 17]. …”

Section: Aimmentioning

confidence: 99%

Laparoscopic minor pancreatic resections (enucleations/atypical resections). A long-term appraisal of a supposed mini-invasive approach.

Costi

Randone²,

Mal³

et al. 2013

Videosurgery and Other Miniinvasive Techniques

Self Cite

View full text Add to dashboard Cite

IntroductionA few retrospective, small, often multicentric studies show encouraging results of laparoscopic minor pancreatic surgery, but do not allow for an evaluation of feasibility and effectiveness.AimEvaluation of the results of laparoscopic minor pancreatic resections (LMPR), including atypical resections and enucleations.Material and methodsThe outcome of all consecutive patients undergoing LMPR in a tertiary care university hospital specializing in the laparoscopic approach to solid organs (I.M.M., Paris – France) was retrospectively evaluated by the analysis of operating time, blood loss, conversion, morbidity, stay and late outcome.ResultsThirty-three patients underwent LMPR (29 enucleations and 4 atypical resections) for various diseases. The conversion rate was 21%, mean operating time 189 min, and mean blood loss 133 ml. Morbidity was 60%; 10 patients (30%) presented a pancreatic fistula. Pancreatic fistula was independent of type of resection, technique of pancreas section, management of enucleated surface and somatostatin administration. Median stay for enucleations was 18 days. Mean follow-up was 61 months.ConclusionsLaparoscopic pancreatic enucleation is feasible and safe, with no mortality, no lengthening of operating time and a high success rate. Conversely, it does not imply a reduction in complications or hospital stay at the present state of the art.

show abstract

“…On the basis of titles and abstracts, a total of 39 potentially pertinent records were detected. Nine additional records were identified by hand searching of bibliographies, for a total of 48 records . After the evaluation of full‐texts, eight studies met all the inclusion criteria and were considered eligible for data extraction and meta‐analysis.…”

Section: Resultsmentioning

confidence: 99%

Minimally invasive versus open pancreatic enucleation. Systematic review and meta‐analysis of surgical outcomes

Guerra

Giuliani

Bencini

et al. 2018

Journal of Surgical Oncology

View full text Add to dashboard Cite

Parenchymal sparing procedures are gaining interest in pancreatic surgery and recent studies have reported that minimally invasive pancreatic enucleation may be associated with enhanced outcomes when compared with traditional surgery. By meta-analyzing the available data from the literature, minimally invasive surgery is not at higher risk of pancreatic fistula and offers a number of advantages over conventional surgery for pancreatic enucleation.

show abstract

Laparoscopic vs open resection of pancreatic endocrine neoplasms: single institution’s experience over 14 years

Abstract: Laparoscopic resection of benign and malignant PENs has similar overall complication and 5-year survival rates as the open technique; however, the laparoscopic approach is associated with shorter operative times.

Cited by 25 publications

References 30 publications

Ressecção laparoscópica dos cistoadenomas pancreáticos

Ressecção laparoscópica dos cistoadenomas pancreáticos

Laparoscopic minor pancreatic resections (enucleations/atypical resections). A long-term appraisal of a supposed mini-invasive approach.

Minimally invasive versus open pancreatic enucleation. Systematic review and meta‐analysis of surgical outcomes

Contact Info

Product

Resources

About