Laparoscopy-Assisted Billroth I Gastrectomy Compared With Conventional Open Gastrectomy

Abstract

Background: Although several studies compare surgical results of laparoscopic and open colonic resections, there is no study of laparoscopic gastrectomy compared with open gastrectomy. Hypothesis: When compared with conventional open gastrectomy, laparoscopy-assisted Billroth I gastrectomy is less invasive in patients with early-stage gastric cancer. Design: Retrospective review of operative data, blood analyses, and postoperative clinical course after Billroth I gastrectomy. Setting: University hospital in Japan. Patients: The study included 102 patients who were treated with Billroth I gastrectomy for early-stage gastric cancer from January 1993 to July 1999: 49 with laparoscopy-assisted gastrectomy and 53 with conventional open gastrectomy.Main Outcome Measures: Demographic features examined were operation time; blood loss; blood cell counts of leukocytes, granulocytes, and lymphocytes; serum levels of C-reactive protein, interleukin 6, total protein, and albumin; body temperature; weight loss; analgesic requirements; time to first flatus; time to liquid diet; length of postoperative hospital stay; complications; proximal margin of the resected stomach; and number of harvested lymph nodes.Results: Significant differences (P<.05) were present between laparoscopy-assisted and conventional open gastrectomy when the following features were compared: blood loss (158 vs 302 mL), leukocyte count on day 1 (9.42 vs 11.14ϫ10 9 /L) and day 3 (6.99 vs 8.22ϫ10 9 /L), granulocyte count on day 1 (7.28 vs 8.90 ϫ 10 9 /L), C-reactive protein level on day 7 (2.91 vs 5.19 mg/dL), interleukin 6 level on day 3 (4.2 vs 26.0 U/mL), serum albumin level on day 7 (35.6 vs 33.9 g/L), number of times analgesics given (3.3 vs 6.2), time to first flatus (3.9 vs 4.5 days), time to liquid diet (5.0 vs 5.7 days), postoperative hospital stay (17.6 vs 22.5 days), and weight loss on day 14 (5.5% vs 7.1%). There was no significant difference between laparoscopy-assisted and conventional open gastrectomy with regard to operation time (246 vs 228 minutes), proximal margin (6.2 vs 6.0 cm), number of harvested lymph nodes (18.4 vs 22.1), and complication rate (8% vs 21%).Conclusions: Laparoscopy-assisted Billroth I gastrectomy, when compared with conventional open gastrectomy, has several advantages, including less surgical trauma, less impaired nutrition, less pain, rapid return of gastrointestinal function, and shorter hospital stay, with no decrease in operative curability. When performed by a skilled surgeon, laparoscopy-assisted Billroth I gastrectomy is a safe and useful technique for patients with earlystage gastric cancer.

Safety and feasibility of laparoscopy-assisted distal gastrectomy with suprapancreatic nodal dissection for clinical stage I gastric cancer: a multicenter phase II trial (JCOG 0703)

“…A body temperature greater than 38 °C is one of the clinical manifestations of systemic infl ammatory response syndrome (SIRS) [26], and patients can suffer greatly from this complication. The change in body temperature was as we expected and was similar to the results of previous reports [27,28].…”

Comparison of laparoscopic versus open gastrectomy for advanced gastric cancer: an updated meta-analysis

“…After reading the full texts of the remaining papers, 24 studies were removed as they only reported the outcomes of LG for AGC whereas no controlled or matched cases treated by OG were available. Among the remaining articles, 19 studies [37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55] were excluded because EGC cases were mixed with AGCs in the cohort studies and data on AGCs were not extractable. Eight studies were further deleted for the following reasons: 2 studies were ongoing randomized controlled trials (RCTs) that only described study design and patient enrollment criteria without results reported [56,57]; 2 studies had overlapped enrollments with former research [58,59]; 1 study reported incomplete data that were not suitable for analysis [60]; and 3 studies discussed other issues irrelevant to the topic of this meta-analysis [61][62][63].…”

Potentially fatal complications for elderly patients after laparoscopy-assisted distal gastrectomy

“…In Japan and Korea, the superiority of laparoscopyassisted gastrectomy (LAG) for early gastric cancer compared with conventional open gastrectomy has been confirmed by both randomized and nonrandomized clinical studies, with advantages including less intraoperative bleeding, less pain, and shorter postoperative hospital stays [4][5][6][7][8][9][10][11][12]. Reported postoperative complication rates are comparable between LAG and conventional open gastrectomy cases.…”