Laparoscopy-Associated Inferior Mesenteric Vein Thrombosis

Lao, Wilson T.; Lee, Chee Hwee; Chan, Wing P.

doi:10.15344/2456-446x/2016/106

Cited by 1 publication

(1 citation statement)

References 3 publications

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“…In addition, it has been reported that MVT of larger distal portions such as portal veins is mediated by local factors, such as malignancy, inflammation and infection while isolated MVT thrombosis is most commonly related to a prothrombotic state that originate from the vena rectae 6–8. There are very few case reports on IMVT, which have revealed associations with diverticulitis, antiphospholipid syndrome, postoperative and SARS-CoV-2 infection without definitive description of pathophysiology 9–13…”

Section: Discussionmentioning

confidence: 99%

Inferior mesenteric vein thrombosis in the setting of testosterone therapy

et al. 2022

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Inferior mesenteric vein thrombosis (IMVT) is a rare and potentially lethal complication that can progress to mesenteric ischaemia if left untreated. We report a case of a man in his 70s with a history of polycythaemia vera (PV) with a known negative Janus kinase-2 mutation (JAK2V617) who was started on testosterone therapy 2 months before presenting with left lower quadrant abdominal and flank pain. Evaluation revealed thrombocytosis and IMVT on CT scan. A non-operative approach was deferred for anticoagulation therapy. Within 24 hours, the patient demonstrated significant clinical improvement, and he subsequently made a full recovery. The patient underwent 6 months of anticoagulation therapy with Apixaban. This case documents the first case of IMVT in the setting of PV and testosterone therapy in the literature.

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Section: Discussionmentioning

confidence: 99%