Laparoskopische Nierenteilresektion bei Nierentumoren

Bier, Simone; Todenhöfer, Tilman; Aufderklamm, Stefan; Hennenlotter, Joerg; Mischinger, Johannes; Sim, Allen; Böttge, J.; Rausch, Steffen; Halalsheh, Omar; Stenzl, Arnulf; Gakis, Georgios; Schwentner, Christian

doi:10.1007/s00120-014-3656-4

Cited by 4 publications

(1 citation statement)

References 25 publications

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“…PN surgery has been widely used as a standard of care for localized small renal tumors, [2,7,11] but factors that affect postoperative renal function have been highlighted in previous researches. [12–14] Warm ischemic time (WIT) has been considered the main factor influencing postoperative renal function after PN for a long period of time, [12,15–17] and some articles [16,18,19] have concluded that IRI was the detriment of renal function after PN surgery in the early postoperative period.…”

Section: Introductionmentioning

confidence: 99%

The correlation between affected renal function and affected renal residual volume

Chen

Jiang

et al. 2019

Medicine

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Laparoscopic nephron-sparing partial nephrectomy with segmental renal artery blocking (SRPN) has been widely used in the treatment of localized renal tumors. However, the impact of ischemia-reperfusion injury (IRI) during SRPN remains controversial. This study aims to evaluate the correlation between affected renal function and affected renal volume after SRPN for localized renal tumor treatment, explore the effect of IRI on renal function after SRPN.A total of 39 patients who underwent SRPN for localized renal tumor from June 2009 to April 2012 were reviewed. These patients were followed-up for 5 years. The preoperative affected renal glomerular filtration rate (aGFRpre), postoperative affected renal glomerular filtration rate (aGFRpost), preoperative affected renal volume (aVolpre), and postoperative affected renal volume (aVolpost) were collected during the follow-up period. The correlation between aGFRpost/aGFRpre and aVolpost/aVolpre was compared.A total of 33 patients were successfully followed up. After 3, 6, 12, 24, and 60 months, aGFRpost was 34.6 ± 4.6, 34.7 ± 4.8, 34.9 ± 4.4, 35.1 ± 4.4, and 35.2 ± 4.2 mL/min. The correlation coefficients between aGFRpost/aGFRpre and aVolpost/aVolpre were 0.659 (P = .000), 0.667 (P = .000), 0.663 (P = .000), 0.629 (P = .000), and 0.604 (P = .000), respectively. The limitation of this study was the small cohort size.For the localized renal tumor, aGFRpost was associated with aVolpost, but was not associated with intraoperative factors, such as the time of clamping of the affected segmental renal artery. As a part of nephrons, the resected tumor tissue caused the lack of inherent nephrons, resulting in the loss of renal function. More nephrons should be maintained before resecting the tumor completely during SRPN.Trial registration: ChiCTR-RRC-17011418.

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Section: Introductionmentioning

confidence: 99%

The correlation between affected renal function and affected renal residual volume

Chen

Jiang

et al. 2019

Medicine

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Therapienebenwirkungen und Nachsorge beim Nierenzellkarzinom

Vahlensieck¹,

Hoffmann²,

Zermann³

2018

Uro-News

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Sozialmedizinische Begutachtung nach operativer und zielgerichteter Therapie des Nierenzellkarzinoms

Vahlensieck

Hoffmann²,

Zermann

2016

Urologe

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In Germany, renal cell cancer counts for 2.5 % of all carcinomas in women and 3.5 % in men. Curative therapy ensures good chances of recovery. But there might be permanent complications like renal insufficiency, pain, incisional hernia, flank muscle relaxation, and paresis. In addition, targeted therapy is associated with several potential side effects. In both therapy groups, severe psychological problems may occur. Still employed patients with these problems must be examined by an expert to estimate the possibilities of returning to working (positive scope of work) and occupations which can not be performed anymore (negative scope of work).

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Laparoskopische Nierenteilresektion bei Nierentumoren

Abstract: LPN is a curative treatment option for the renal cell carcinoma similar to open partial nephrectomy; however, laparoscopy is associated with lower morbidity.

Cited by 4 publications

References 25 publications

The correlation between affected renal function and affected renal residual volume

The correlation between affected renal function and affected renal residual volume

Therapienebenwirkungen und Nachsorge beim Nierenzellkarzinom

Sozialmedizinische Begutachtung nach operativer und zielgerichteter Therapie des Nierenzellkarzinoms

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