In this paper, we prove the large data scattering for fractional nonlinear Schrödinger equations (FNLS) on waveguide manifolds R d × T, d ≥ 3. This result can be regarded as the fractional analogue of [43,44] and the waveguide analogue of [16]. A key ingredient of the proof is a Morawetz-type estimate for the setting of this model. This result also extends the recent result [35] by proving the scattering behavior.