The aim of this study is tree-fold. First, we investigate the thermodynamics of the Ising models with respect to 2-multiple Hamiltonians. This extends the previous results of [Chazotte and Redig, Electron. J. Probably., 2014] to N d . Second, we establish the large deviation principle (LDP) of the average 1 N S G N , where S G N is a 2-multiple sum along a semigroup generated by k numbers which are k co-primes. This extends the previous results [Ban et al. Indag. Math., 2021] to a board class of the long-range interactions. Finally, the results described above are generalized to the multidimensional lattice N d , d ≥ 1.