At present, the wind tunnel experiment is more and more widely used, but it is rarely used in the construction industry. Therefore, this thesis is to study the wind load of prefabricated buildings by numerical simulation. First, the application field of wind load numerical simulation is analyzed. Next, the numerical model is used to simulate the average wind pressure distribution on the building surface of single tower, tower G and tower F. The turbulence model is established based on fluid mechanics, which makes the obtained data more accurate and can converge quickly. Finally, the wind load interference effects of two fabricated towers and a single tower are analyzed. The experimental results show that the moment coefficient interference factor of tower F remains between 0.696~1.125 and that of tower G remains between 0.291~1.043. When the wind direction angle is 90°, the maximum values of the building base torque and the base bending moment around the X axis appear simultaneously, and the moment around the Y axis is not 0, which will change the stress of the building on the base. If the wind direction angle becomes 0°, the two fabricated towers will interact to reduce the impact on the base moment of the upstream building. Meanwhile, the wind pressure interference factor on the wall surface of prefabricated buildings remains between [-1, 1.5]. When the buildings in the upstream are blocked, the wind pressure interference factor may become 0. However, the shape coefficient of negative pressure on the inner wall of the building will increase rapidly due to the narrow channel effect. This thesis will analyze the wind load on the surface of prefabricated buildings through numerical simulation, which will help the wind engineering team build safer prefabricated buildings.