We assess the viability of a recently proposed novel approach to LES for compressible variable density flows by means of a priori tests. The a priori tests have been carried out filtering a twodimensional DNS database of the classic lock-exchange benchmark.The tests confirm that additional terms should be accounted for in subgrid scale modeling of variable density flows, with respect to the terms usually considered in the traditional approach. Several alternatives for the modeling of these terms are assessed and discussed.