“…Its overall complication rate stands at around 6.85 % with a morbidity of between 6.27 % and 7.51 % and a case-fatality rate of up to 21.4 % [ 1 , 2 ]. HSH is an uncommon but dreaded post-ERCP complication, until now, 67 cases have been reported worldwide and its mechanism is still unclear, so the identification of risk factors, patterns of presentation and successful treatment approaches may improve the safety and efficacy of medical procedures [ [3] , [4] , [5] , [6] , [7] , [8] , [9] ]. In this case series, this study presents two cases of post-ERCP HSH, a procedure indicated by a diagnosis of choledocholithiasis, one ruptured and one non-ruptured, which occurred at the same center and in the same month.…”