Large mucinous adenoma of pancreas presenting with recurrent pancreatitis

Paramhans, D.; Shukla, Satish; Mathur, Rajkumar; Satsangi, Bhaskar; Batra, Ankur

doi:10.4318/tjg.2011.0166

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…Recurrent acute and chronic pancreatitis are reported commonly in patients with IPMN. However, few cases of MCN with pancreatitis are also reported 12,13,14 . Coexistence of MCN and pseudocyst is also very rare and two such cases were reported previously 15,16 .…”

Section: Introductionmentioning

confidence: 99%

Invasive Adenoarcinoma Arising in Mucinous Cystic Neoplasm Communicating to Main Pancreatic Duct with Concurrent Pseudocyst: A Report of Very Rare Case

Kumar

Pottakkat

Gnanasekaran

et al. 2022

Preprint

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Purpose: MCN communicating with pancreatic duct and co-existence of pancreatic pseudocyst with MCN are rare conditions. Malignant transformation in MCN is not uncommon but combination of these rare presentations is very rare and has not been reported previously. Methods - A Case report of malignant transformation of MCN, which was communicating to MPD with concurrent pseudocyst of pancreas. Results-Two communicating large cysts in relation of tail of pancreas and lesser sac were diagnosed in a 45-year-old woman who had symptoms of early satiety and postprandial fullness of abdomen with history of recurrent acute pancreatitis.On cross sectional imaging there were two cysts:one multiloculated cyst with internal enhancing septations and solid component, which was communicating to main pancreatic duct and other uniloculated cyst without solid component or sepatations.Preoperative diagnosis of an IPMN with co-existing pseudocyst was made. En-bloc resection of both cysts, distal pancreas-spleen, proximal stomach and left hemidiaphragm with lymphadenectomy was done owing to high risk of malignancy. Final diagnosis on histopathological examination was moderately differentiated grade 2, MCN with invasive adenocarcinoma with coexisting pseudocyst of pancreas. Conclusion: We are reporting the 1st case of invasive adenocarcinoma arising in MCN, which was communicating to main pancreatic duct with chronic pancreatitis and co-existing pseudocyst of pancreas.This case provides unique opportunity to study spectrum of cystic lesions of pancreas in single case.

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Section: Introductionmentioning

confidence: 99%

Invasive Adenoarcinoma Arising in Mucinous Cystic Neoplasm Communicating to Main Pancreatic Duct with Concurrent Pseudocyst: A Report of Very Rare Case

Kumar

Pottakkat

Gnanasekaran

et al. 2022

Preprint

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“…However, in case of an acute pancreatitis due to the cystic tumor enzymes (amylase and lipase) levels are also elevated. In IPMNs, increased enzymes levels reflect communication of the cystic tumor with the main pancreatic duct or its branch [35]. Differential diagnosis of all pancreatic cysts is presented in Table 4.…”

Section: Diagnosis Of Pancreatic Cystsmentioning

confidence: 99%

Pancreatic cysts: etiology, diagnosis and management

Jabłońska

2014

Open Medicine

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AbstractPancreatic cysts involve a wide spectrum of pathologies from post-inflammatory cysts to malignant neoplasms. Pancreatic pseudocysts, serous cystadenomas, mucinous cystadenomas, intraductal papillary mucinous neoplasms (IPMNs) and solid pseudopapillary tumors occur most frequently. Differential diagnosis involves the following imaging investigations: transabdominal ultrasonography (TUS), contrast enhanced ultrasonography (CEUS) and endoscopic ultrasonography (EUS), computed tomography (CT), magnetic resonance (MR) and magnetic resonance cholangiopancretography (MRCP), endoscopic retrograde cholangiopancretography (ERCP). The cyst fluid cytology is performed in difficult differential diagnosis between pseudocysts and benign and potentially malignant or malignant tumors. Most frequently, viscosity, amylase, CEA and CA 19-9 levels are determined. Imaging findings should be correlated with cytology. The management depends on the cyst type and size. Small asymptomatic pseudocysts, serous cystadenomas and branchduct IPMNs should be carefully observed, whereas symptomatic large or uncertain serous cystadenomas and cystadenocarcinomas, mucinous cystadenomas and cystadenocarcinomas, main-duct IPMNs and large branch-duct IPMNs with malignant features, serous and mucinous cystadenocarcinomas, and solid pseudopapillary tumors require surgery. Pseudocysts are usually drained. Percutaneous / EUS-guided or surgical cyst drainage can be performed. Complicated and uncertain pseudocysts and cystic tumors need surgical resection. The type of surgery depends on cyst location and size and includes proximal, central, distal, total pancreatectomies and enucleation.

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Large mucinous adenoma of pancreas presenting with recurrent pancreatitis

Cited by 2 publications

References 4 publications

Invasive Adenoarcinoma Arising in Mucinous Cystic Neoplasm Communicating to Main Pancreatic Duct with Concurrent Pseudocyst: A Report of Very Rare Case

Invasive Adenoarcinoma Arising in Mucinous Cystic Neoplasm Communicating to Main Pancreatic Duct with Concurrent Pseudocyst: A Report of Very Rare Case

Pancreatic cysts: etiology, diagnosis and management

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