Large mural thrombus in the non-aneurysmal and non-atherosclerotic ascending aorta: a case report

Dai, Xiaoyi; Ni, Chengyao; Luo, Wei; Miao, Shuying

doi:10.1186/s13019-021-01585-w

Cited by 4 publications

(2 citation statements)

References 9 publications

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“…There are also warnings that the adenovirus vector vaccine ChAdOx1 nCoV-19 can result in the rare development of immune thrombotic thrombocy-topenia mediated by platelet-activating antibodies against PF4, which clinically mimics autoimmune heparin-induced thrombocytopenia [8,9]. Aortic thrombosis has been described in case reports of patients with COVID-19 and is associated with important complications [10][11][12]. One study suggests that the occurrence of the synchronous damage involving both the lumen surface (endothelial dysfunction, endotheliitis, and endothelial detachment) and the adventitia (inflammation and occlusive thrombosis of vasa vasorum) could be the key points related to the fatal outcome in patients with SARS-CoV-2 [13].…”

Section: Introductionmentioning

confidence: 99%

Aortic Thrombosis Associated with Three Types of COVID-19 Vaccine

de Godoy,

Neto,

da Silva

et al. 2023

Case Reports in Surgery

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Aortic thrombosis has been studied little in patients with COVID-19 and an association has recently been reported with the vaccine for this disease. The aim of the present study is to report five cases of aortic thrombosis at our institution within a three-month period associated with the COVID-19 vaccine. Five cases of aortic thrombosis were evaluated—three women and two men aged 29, 49, 51, 60, and 79 years. Four thrombi involved the thoracic aortic and one involved the abdominal aorta, with embolisms found in the kidneys, spleen, liver, upper limbs, and lower limbs. Embolectomy was performed on the limbs, and anticoagulant therapy was performed for the abdominal arteries. The patients recovered well and anticoagulant therapy was maintained. Aortic thrombosis is uncommon but was associated with the AstraZeneca vaccine in this case series.

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Section: Introductionmentioning

confidence: 99%

Aortic Thrombosis Associated with Three Types of COVID-19 Vaccine

de Godoy,

Neto,

da Silva

et al. 2023

Case Reports in Surgery

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“…The caudal half of the body and important abdominal organs depend on the integrity of the abdominal aorta, a significant circulatory structure, to survive and function. The end organs may exhibit either an acute or chronic disease when there is a subtle irregularity in the abdominal aorta and its branches [4][5][6]. Many disorders can affect the abdominal aorta; some more prevalent ones are atherosclerosis, dissections, aneurysms, and aorto-arteritis.…”

Section: Introductionmentioning

confidence: 99%

Optimising anesthesia support during operations on the abdominal aorta and its branches

2022

FEM

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Background: Pathology of the aorta includes aortic aneurysms, coarctation, dissection, atherosclerotic disease, and aortitis. The only two evidence-based treatment options for abdominal aortic repair are endovascular and open surgery. The anesthetic approach and medications may impact the outcomes of the surgical repair of the abdominal aorta and its branches. Aim: to evaluate the use of various analgesic regimens and local, regional, or general anesthesia in "optimising" surgical outcomes in patients undergoing surgical repair of the abdominal aorta and its branches. Methods: In this review, English studies from common databases such as Pubmed/MEDLINE, Google Scholar, Web of Science, Scopus, and the Cochrane Library with the keywords "Abdominal aorta," "operations," "aortic branches," combined with keywords, involving " anesthesia were involved." The end date for this review was November 2022. Scientific novelty: Recent scientific studies have focused on the use of advanced monitoring technologies such as cerebral oximetry and microdialysis to improve the safety and efficacy of anesthesia management in aortic surgery. These technologies provide more accurate and real-time information about cerebral perfusion and metabolism, allowing the anesthesiologist to identify and manage potential complications such as cerebral ischemia more effectively. Additionally, the use of pharmacological agents such as dexmedetomidine and remifentanil has been shown to reduce the risk of postoperative delirium and cognitive dysfunction, further improving patient outcomes. Conclusion: Aortic surgery is a complex and high-risk procedure that requires careful management of anesthesia to ensure patient safety and optimal outcomes. With ongoing advances in anesthesia techniques and monitoring technologies, there is reason to be optimistic about the future of aortic surgery and the prospects for improved patient outcomes. The anesthesiologist plays a critical role in this process, working closely with the surgical team to provide safe and effective anesthesia throughout the procedure and ensuring that the patient receives appropriate pain management and other supportive care in the postoperative period

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A giant free-floating thrombus in the ascending aorta caused by radiofrequency ablation of premature ventricular contractions

Chen

et al. 2022

European Journal of Cardio-Thoracic Surgery

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Large mural thrombus in the non-aneurysmal and non-atherosclerotic ascending aorta: a case report

Cited by 4 publications

References 9 publications

Aortic Thrombosis Associated with Three Types of COVID-19 Vaccine

Aortic Thrombosis Associated with Three Types of COVID-19 Vaccine

Optimising anesthesia support during operations on the abdominal aorta and its branches

A giant free-floating thrombus in the ascending aorta caused by radiofrequency ablation of premature ventricular contractions

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