Large ovarian endometriomas are associated with high pre-operative anti-Müllerian hormone concentrations

Roman, Horace; Chanavaz-Lacheray, Isabella; Mircea, Oana; Berby, Benoît; Dehan, Lise; Braund, Sophia; Verspyck, É.; Puşcaşiu, Lucian

doi:10.1016/j.rbmo.2020.09.008

Cited by 13 publications

(10 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pregnancy rates in studies comparing women managed by either cystectomy or ablation using CO 2 laser varied from, respectively, 38.1% and 44.4% at 5 years after the surgery 22 to, respectively, 72.2% and 74.3% after a mean follow up averaging 3 years 10 . Case series including women undergoing ovarian ablation by plasma energy and getting pregnant in up to 73% of cases were reported by our team, and this study population may partially overlap with the one included in this study 23,24 …”

Section: Discussionmentioning

confidence: 86%

“…10 Case series including women undergoing ovarian ablation by plasma energy and getting pregnant in up to 73% of cases were reported by our team, and this study population may partially overlap with the one included in this study. 23,24 We should emphasize that a majority of women managed by ablation and simple drainage underwent surgical procedures for deep endometriosis involving the digestive tract. We believe our results to be of interest for those colleagues inquiring whether women with severe deep endometriosis and pregnancy wish would benefit more from first-line ART to increase postoperative pregnancy rate.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pregnancy rate following endometriomas management by ablation using plasma energy, cystectomy and drainage: A three‐arm comparative study

Puşcaşiu

Mircea

Hennetier

et al. 2022

Intl J Gynecology & Obste

Self Cite

View full text Add to dashboard Cite

Objective To compare differences in the postoperative pregnancy rate in women seeking to conceive and presenting with endometriomas larger than 3 cm in diameter, which were managed by ablation using plasma energy, cystectomy, or simple drainage. Methods A retrospective three‐arm comparative study based on prospective collection of data evaluating 363 patients, undergoing endometrioma cystectomy, ablation using plasma energy, or simple drainage. Results In this series, 204 (56.2%) patients underwent endometrioma ablation using plasma energy, 121 (33.3%) received cystectomy, and 38 (10.5%) had a simple drainage. Postoperative follow up was 50 ± 26 months. Overall postoperative pregnancy rate was 60.3%. The probability of being pregnant after cystectomy, ablation, and drainage was respectively 27%, 32%, and 16% at 12 months, with a statistically significant difference between pregnancy rates among the three arms (P = 0.015). Simple drainage was associated with a probability of conception over 50% after 2 years, mainly based on postoperative assisted reproductive technology. Conclusions We reveal good postoperative pregnancy rate after ablation using plasma energy or cystectomy for endometriomas. Surgical management should be carefully considered in women with endometriomas and pregnancy intention, because the postoperative pregnancy rate may be compared with that observed after first‐line assisted reproductive technology management.

show abstract

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Pregnancy rate following endometriomas management by ablation using plasma energy, cystectomy and drainage: A three‐arm comparative study

Puşcaşiu

Mircea

Hennetier

et al. 2022

Intl J Gynecology & Obste

Self Cite

View full text Add to dashboard Cite

show abstract

“…Despite the negative relationship between endometriosis and circulating AMH reported by several studies, two reports found an increasing serum AMH level with endometrioma size [37,38]. If this finding will be confirmed by future studies, a possible explanation is a different impact of endometrioma on AMH production…”

Section: The Predictive Value Of Amh For Oocyte Yield In Endometriosismentioning

confidence: 79%

The Impact of Endometriosis on Controlled Ovarian Stimulation Outcome

Albu¹,

Albu²

2022

Endometriosis - Recent Advances, New Perspectives and Treatments

View full text Add to dashboard Cite

Endometriosis, a frequent condition in reproductive age women, is also associated with infertility by mechanisms incompletely clarified. The effectiveness of endometriosis treatment for infertility is debated, being possible that in vitro fertilization (IVF) offers a better alternative. The response to controlled ovarian stimulation (COS) is an important predictor of live birth, but it might be affected in endometriosis possibly through a decrease of ovarian reserve. Moreover, the predictive value of anti-mullerian hormone (AMH) for the response to COS could be altered by factors disrupting the AMH production in endometriosis. Therefore, we aim to review the literature regarding the response to COS and the AMH production and their predictive value for COS response in patients with endometriosis.

show abstract

“…While there are multiple studies demonstrating that merely the presence of an ovarian endometrioma is associated with reduced AMH levels compared to non‐endometriosis ovarian cysts, 24 there is also a recent study that supports that large ovarian endometriomas (>6 cm) are associated with high pre‐operative AMH concentrations 26 …”

Section: Discussionmentioning

confidence: 99%

Impact on ovarian reserve after minimally invasive single‐port laparoscopic ovarian cystectomy in patients with benign ovarian cysts: A systematic review and meta‐analysis

Tsiampa

Spartalis

Tsourouflis

et al. 2021

Int J Clinical Practice

View full text Add to dashboard Cite

Benign ovarian cysts are very common in women of reproductive age and often require surgical excision, particularly when they cause symptoms or infertility. 1 However, there has been a growing concern over the possible damaging effects that this procedure may cause on the ovarian reserve. 2,3 The continuous development of technology and minimally invasive techniques during the recent years, has helped establish laparoscopic ovarian cystectomy as the first-line treatment for benign ovarian tumours, such as symptomatic endometriomas, dermoid cysts or serous cystadenomas. 4 Due to favourable surgical outcomes, fewer complications, less pain, and improved cosmetic results, laparoscopic cystectomy has essentially replaced open surgery. 5 Nevertheless, several studies have indicated that laparoscopic ovarian cystectomy is associated with a decreased ovarian reserve and for this reason there has been much debate about the most suitable laparoscopic approach that causes the least amount of damage to the ovarian reserve after surgery. [6][7][8][9] A recent advancement in the field of minimally invasive gynaecology is transumbilical single-port laparoscopy (SPL). This minimally invasive approach to surgery requires only one entry point, typically through the umbilical region. In particular, the use of SPL has not only been proposed in adnexal disease but in endometriomas excision as well. 10 Several clinical reports that have been conducted indicate that a limited operative space in SPL causes unstable camera motion and interference between instruments which may increase the difficulty and risk of surgery. 11,12 Yoon et al, Huang et al and Wang et al found that the ovarian reserve did not statistically differ

show abstract

Large ovarian endometriomas are associated with high pre-operative anti-Müllerian hormone concentrations

Cited by 13 publications

References 24 publications

Pregnancy rate following endometriomas management by ablation using plasma energy, cystectomy and drainage: A three‐arm comparative study

Pregnancy rate following endometriomas management by ablation using plasma energy, cystectomy and drainage: A three‐arm comparative study

The Impact of Endometriosis on Controlled Ovarian Stimulation Outcome

Impact on ovarian reserve after minimally invasive single‐port laparoscopic ovarian cystectomy in patients with benign ovarian cysts: A systematic review and meta‐analysis

Contact Info

Product

Resources

About