Large ovarian tumors in adolescents, a systematic review of reported cases, diagnostic findings and surgical management

Grigore, Mihaela; Murarasu, Mara; Himiniuc, Loredana; Toma, Bogdan Florin; Duma, Odetta; Popovici, Răzvan

doi:10.1016/j.tjog.2021.05.005

Cited by 13 publications

(17 citation statements)

References 47 publications

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“…Adolescents with a symptomatic ovarian mass include abdominal pain, menstrual disturbances, and an enlarged abdomen. Other complications can be accompanied by signs and symptoms that lead to compression, such as nausea, vomiting, weight loss or increased frequency of urination, urinary retention due to cysts pressing on the ureteral tract which can cause hydronephrosis, compression of the rectum so that the patient is constipated and dyspnea, torsion, intestinal infection or obstruction, and constitute a surgical emergency ( 9 , 10 ).…”

Section: Discussionmentioning

confidence: 99%

“…This patient had an ultrasound examination, which indicated an adnexal mass on the right ovary, and a CT-scan was performed to further analyze this mass. A cyst may be classified as benign if at least one ultrasound feature of a benign mass (B-feature: unilocular cyst, presence of solid components where the largest component <7 mm, presence of acoustic shadowing Smooth multilocular tumour with largest diameter <100 mm, no blood flow) is present, and none of the ultrasound features of malignancy ( 10 ). CT scan of the abdomen revealed a giant septal and lobulated cyst (30.7 cm × 30.72 cm × 31.67 cm), oval-shaped, located in abdominal and pelvis and abdominal cavity.…”

Section: Discussionmentioning

confidence: 99%

“…), the surgeon may change the procedure to an open laparotomy. Laparoscopically in giant ovarian cysts, especially those that reach the umbilicus, there is a risk of perforation when the trocar is inserted ( 10 ). In this case report, open salpingo- oophorectomy was done, without any perioperative complications.…”

Section: Discussionmentioning

confidence: 99%

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A Giant Ovarian Cystadenoma in A 20-Year-Old Nulliparous Woman: A Case Report

et al. 2022

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Giant ovarian cyst itself is defined as a cyst >10 cm in diameter from radiological- examination or the size of the cyst exceeds the umbilicus. Extra-large benign and malignant cysts of the ovary are uncommon and involve diagnostic and management challenges. We present the case of a 20-year-old nulliparous woman who was referred to our center with complaints of abdominal pain and heavy breathing. She benefited from a salphingo-oophorectomy laparotomy procedure. Benign and malignant gynecologic and non-gynecologic etiologies are included in the differential diagnosis of an abdominal mass. Because of the infrequent occurrence or absence of distinctive clinical presentation of the giant ovarian cyst, accurate preoperative diagnosis is challenging.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A Giant Ovarian Cystadenoma in A 20-Year-Old Nulliparous Woman: A Case Report

et al. 2022

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“…Los tumores ováricos pueden ser asintomáticos hasta que se observa un aumento del perímetro abdominal. También pueden acompañarse de signos y síntomas sugestivos de compresión, como náuseas, vómitos, pérdida de peso o aumento de la frecuencia urinaria, retención urinaria, estreñimiento y disnea (26)(27)(28)(29) .…”

Section: Discussionunclassified

Caracteristicas epidemiológicas, clínicas histopatológicas y quirúrgicas en adolescentes con tumoración de ovario de un hospital nacional

Cabrera

2022

Ágora

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Objetivo: Determinar las características epidemiológicas, clínicas, histopatológicas y quirúrgicas en adolescentes con tumoración de ovario de un Hospital Nacional. Materiales y métodos: El estudio es de tipo descriptivo, retrospectivo y transversal. Se contó con una población de 63 pacientes. La técnica de recolección de datos se dio a través de fichas previamente elaboradas en donde se plasmaban los datos de las historias clínicas. Resultados: En cuanto a las características epidemiológicas se obtuvo que la edad de mayor frecuencia fue entre 11 a 18 años 85% (n=63), dentro de las características clínicas, la sintomatología más frecuente fue el dolor abdomino pélvico 96% (n=63), además dentro de las características histopatológicas, el tumor más frecuente fue el tipo Endometriosico 47% (n=63) y la cirugía que se realizó con mayor frecuencia fue la laparotomía 61% (n=63). Conclusiones: Los tumores de ovario en niñas y adolescentes tienen una frecuencia de 1,5% de acuerdo a su tipo de presentación, su forma de presentación aun es atípica, la gran mayoría de tumores son de tipo benigno, la cirugía que mayormente se realizo fue la laparotomía abierta.

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“…Although epithelial ovarian cancer is the most predominant pathological subtype in adults, ovarian tumours in children and adolescents originate mainly from non-epithelial tissues and cells that are specific to the ovary. Specifically, about 85% of all preadolescent malignant ovarian masses are germ cell tumours (GCTs), 8% are epithelial cell carcinomas, 5% are sex cord stromal tumours (SCSTs) and steroid cell tumours, while less than 1% of them are small cell carcinomas of the ovary [ 4 , 8 , 9 ]. Germ cell tumours are the most common ovarian neoplasms in pediatric patients, with dysgerminomas and yolk sac tumours being accordingly the most prominent seminomatous and nonseminomatous GCTs in this population [ 10 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Management and Prognostic Factors for Ovarian Malignant Tumours in Adolescents: A Comprehensive Review of Current Guidelines

et al. 2023

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Background: Ovarian malignant tumours are rarely diagnosed in adolescents but may have a significant impact on their survival, future fertility and quality of life. The management of such cases is rather complex and requires expertise and careful planning according to scarce existing evidence and recommendations. Objective: The aim of this study was to review and compare recommendations from published guidelines regarding the diagnosis, prognosis and treatment of malignant ovarian tumours in adolescents. Evidence acquisition: A comparative descriptive/narrative review of guidelines issued by L’Observatoire des Tumeurs Malignes Rares Gynécologiques, the British Society for Paediatric & Adolescent Gynaecology, the European Society for Medical Oncology, the European Society of Gynecological Oncology-European Society for Paediatric Oncology and the European Cooperative Study Group for Pediatric Rare Tumors was conducted. Results: All guidelines recommend a thorough diagnostic work-up, consisting of both imaging tests and serum tumour marker measurement, as well as the use of immunohistochemical methods to confirm the diagnosis and complete surgical staging prior to constructing the treatment plan. There is a lack of recommendations regarding the assessment of prognostic factors, with only one guideline providing detailed information. Treatment strategies, as suggested by the majority of guidelines and with only a few discrepancies between them, should include both surgery and adjuvant therapies, mainly chemotherapy, with great emphasis on fertility preservation when it is considered oncologically safe and on the significance of regular and long-term follow-up. Conclusions: There is a significant degree of agreement among recommendations of existing guidelines. The reported differences, although limited, highlight the need for the adoption of an international consensus in order to further improve the management of adolescent ovarian cancer.

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Large ovarian tumors in adolescents, a systematic review of reported cases, diagnostic findings and surgical management

Cited by 13 publications

References 47 publications

A Giant Ovarian Cystadenoma in A 20-Year-Old Nulliparous Woman: A Case Report

A Giant Ovarian Cystadenoma in A 20-Year-Old Nulliparous Woman: A Case Report

Caracteristicas epidemiológicas, clínicas histopatológicas y quirúrgicas en adolescentes con tumoración de ovario de un hospital nacional

Therapeutic Management and Prognostic Factors for Ovarian Malignant Tumours in Adolescents: A Comprehensive Review of Current Guidelines

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