Large Pancreatic Lipoma Causing Duodenal Obstruction

Walker, Brett S.; Davis, Jessica L.; Mayo, Skye C.

doi:10.1007/s11605-020-04773-6

Cited by 7 publications

(5 citation statements)

References 3 publications

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“…One such category is that of severe abdominal pain related to torsion of lipomas related to the sigmoid colon and torsion of a pedunculated lipoma arising from the abdominal wall overlying the right iliac fossa, mimicking acute appendicitis [6]. Another clinical presentation associated with these large intra-abdominal lipomas was symptoms of intestinal obstruction [7,8].…”

Section: Discussionmentioning

confidence: 99%

Mass Effect of Large Pelvic Lipoma Resulting in Femoral Hernia

Clifford,

Gadoura,

Ishola

et al. 2024

Cureus

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A 73-year-old lady presented with a three-day history of constipation, vomiting, and abdominal pain. On examination, a right femoral hernia was identified, and this was confirmed on computed tomography imaging with evidence of mechanical small bowel obstruction. There was an incidental finding of a large pelvic lipoma causing a mass effect. This lady underwent open repair of the femoral hernia. Intra-abdominal lipomatosis is a rare finding and can present itself in a variety of manifestations, or it can be identified as an incidental finding on cross-sectional imaging. Bowel obstructions, abdominal pain, lipoma, and abdominopelvic hernias are some examples of symptomatic presentations of intra-abdominal lipomas.

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Section: Discussionmentioning

confidence: 99%

Mass Effect of Large Pelvic Lipoma Resulting in Femoral Hernia

Clifford,

Gadoura,

Ishola

et al. 2024

Cureus

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“…In most of the cases reported in the literature, lesions are located at the head of the pancreas (Aithal Sitharama et al, 2016;Ferrozzi et al, 2000;Gossner, 2014;Hois et al, 2006;Katz et al, 1998;Monte et al, 2006;Stadnik et al, 2012;Walker et al, 2021). In only some cases it was found on different places such as the neck of the pancreas (Kawahata et al, 2017), the tail (Gossner, 2014;Katz et al, 1998;Secil et al, 2001), the body (Gossner, 2014), and body-tail junction (Bülbül et al, 2013;Hois et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

“…The true incidence of pancreatic lipomas is not known exactly. However, as a result of retrospective studies, the rate of pancreatic lipomas in asymptomatic patients was reported as between 0.08-0.012% (Butler et al, 2016;Hois et al, 2006, Walker et al, 2021.…”

Section: Case Reportmentioning

confidence: 99%

“…In addition to this, when pancreatic lipomas do not compress on ductus pancreaticus and ductus choledochus, it is known as an asymptomatic (Secil et al, 2001;Stadnik et al, 2012). Walker et al (2021) reported that the majority of pancreatic lipomas are asymptomatic and can be treated without surgical intervention. However, they stated that if pancreatic lipomas are large, they can show symptomatic symptoms (abdominal pain and obstructive symptoms) and these symptoms can be treated with pancreatic resection.…”

Section: Introductionmentioning

confidence: 99%

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CT Finding of Pancreatic Lipoma: A Case Report

Keleş¹,

Yılmaz²,

Kadıyoran³

2021

jgehes

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The pancreas is a very important mixed gland in the alveolar structure that secretes both internally and externally. While the pancreas secretes glucagon, insulin and somatostatin hormones (endocrine) into the blood, it secretes amylase, lipase and trypsin enzymes (exocrine) to the second part of the duodenum. It has 4 sections of head of the pancreas, neck of pancreas, body of pancreas, and tail of pancreas. Pancreatic lipomas are rare lesions that are usually detected incidentally on imaging methods. It has been reported in the literature that if the lesion is uncompressed and not large, it is usually asymptomatic. In our article, in the axial abdominal computed tomography examination obtained following intravenous (IV) and oral contrast agent administration in a patient who was followed up for breast cancer; A nodular lesion with a fat density of approximately 4 centimeters localized at the level of the uncinate process of pancreas was detected. It is thought that this lesion is a pancreatic lipoma. Our study described the computed tomography imaging features of pancreatic lipoma, its differential diagnosis, and a brief review of the relevant literature. In addition, we think that our study may be useful for radiologists and surgeons in the diagnosis and follow-up of the lesion.

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“…Although lipomas are one of the most common benign mesenchymal tumors, pancreatic lipomas (PLs), arising from adipose tissue in the pancreatic parenchyma, are extremely rare among pancreatic tumors [ 1 ]. Previous studies have reported that 0.012–0.08% of consecutive patients undergoing computed tomography (CT) or magnetic resonance imaging (MRI) were incidentally diagnosed with PL; however, the accurate incidence of PL remains unclear [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Pancreatic ductal adenocarcinoma arising from the pancreatic parenchyma compressed by a huge pancreatic lipoma: a case report

et al. 2023

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Background Pancreatic lipomas (PLs) arising from the adipose tissue in the pancreatic parenchyma are rare among pancreatic tumors. Coexisting pancreatic ductal adenocarcinoma (PDAC) and PLs have not been previously reported. Herein, we report a case of PDAC arising from the pancreatic parenchyma with chronic pancreatitis compressed by a large PL. Case presentation The patient was a 69-year-old male. He had been diagnosed with a PL using computed tomography (CT) 12 years previously. The tumor had been slowly growing and was followed up carefully because of the possibility of well-differentiated liposarcoma. During follow-up, laboratory data revealed liver damage and slightly elevated levels of inflammatory markers. Contrast-enhanced CT revealed the previously diagnosed 12 cm pancreatic head tumor and an irregular isodensity mass at the upper margin of the tumor that invaded and obstructed the distal common bile duct. Magnetic resonance cholangiopancreatography demonstrated no specific findings in the main pancreatic duct. Based on these imaging findings, the patient underwent endoscopic retrograde biliary drainage and bile duct brushing cytology, which revealed indeterminate findings. The differential diagnosis of the tumor at that time was as follows: (1) pancreatic liposarcoma (focal change from well-differentiated to dedifferentiated, not lipoma), (2) distal cholangiocarcinoma, and (3) pancreatic cancer. After the cholangitis improved, a pancreatoduodenectomy was performed. Histologically, hematoxylin–eosin staining revealed moderately differentiated PDAC compressed by proliferating adipose tissue. The adipose lesion showed homogeneous adipose tissue with no evidence of sarcoma, which led to a diagnosis of lipoma. Additionally, extensive fibrosis of the pancreatic parenchyma and atrophy of the acinar cells around the lipoma was suggestive of chronic pancreatitis. The pathological diagnosis was PDAC (pT2N0M0 pStage Ib) with chronic pancreatitis and PL. The postoperative course was uneventful, and the patient was discharged on the 15th day after surgery. The patient received adjuvant chemotherapy and has remained recurrence-free for more than 6 months. Conclusions PL may be associated with the development of PDAC in the surrounding inflammatory microenvironment of chronic pancreatitis. In cases of growing lipomas, careful radiologic surveillance may be needed not only for the possibility of liposarcoma but also for the coincidental occurrence of PDAC.

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Large Pancreatic Lipoma Causing Duodenal Obstruction

Cited by 7 publications

References 3 publications

Mass Effect of Large Pelvic Lipoma Resulting in Femoral Hernia

Mass Effect of Large Pelvic Lipoma Resulting in Femoral Hernia

CT Finding of Pancreatic Lipoma: A Case Report

Pancreatic ductal adenocarcinoma arising from the pancreatic parenchyma compressed by a huge pancreatic lipoma: a case report

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