Large paraspinal abscess as a complication of infliximab therapy in Crohn’s disease

Abstract

We report a 36-year-old man who developed a large epidural and paraspinal abscess as a complication of infliximab therapy being used for underlying Crohn’s disease. Cultures of the collection grew methicillin-susceptible Staphylococcus aureus, and treatment consisted of abscess drainage, prolonged intravenous and oral flucloxacillin and temporary withholding of his infliximab. While infection-related complications are well described with infliximab therapy, this is the first description of a large paraspinal abscess with epidural extension.

Painless Peri-Tonsillar Abscess in a Pediatric Patient: Case Report and Review of the Literature

“…To our knowledge, infliximab has not been previously associated with the formation of peritonsillar abscesses, however it has been reported by Nithianandan et al as a causative agent for a large paraspinal abscess extending to the epidural space in one of the patients with a history of Crohn's disease. [6].…”