Large Placental Chorioangioma as a Cause of Sudden Intrauterine Fetal Death

Abstract

A giant placental chorioangioma was diagnosed in a fetus at 22 weeks of gestation by prenatal ultrasound screening and color Doppler imaging. Although no signs of fetal hydrops and cardiac decompensation were observed, the situation of the fetus deteriorated rapidly and in utero fetal death occurred at 26 weeks, attributed to bleeding from ruptured sinusoids within the tumor. Prenatal diagnosis of chorioangioma and treatment modalities are discussed.

Histopathologic findings in multicentric placental chorangioma with trophoblastic proliferation in a sheep

“…Hyalinisation, necrotic and calcified foci were the other findings. In the current case, our findings were consistent with previous studies in humans and animals (Kirkbride et al, 1973;Batukan et al, 2001;Kurman, 2002;Fox, 2003). We reported chorangioma associated with trophoblastic proliferation in a sheep.…”

“…Polyhydramnia, preterm delivery and increased toxaemia may occur in pregnant patients (Bashiri et al, 1998;Taori et al, 2008). The foetus could be affected by nonimmune hydrops, cardiomegaly, congestive cardiac failure, circulatory disturbances (anaemia, thrombocytopenia, consumptive coagulopathy) and growth defects (prematurity, growth retardation) (Demiriz et al, 1997;Sepulveda et al, 2000;Batukan et al, 2001).…”

Chorioangioma of placenta: Sonographic features

“…[6][7][8] Sonography is the mainstay in diagnosing chorioangioma, which appears on gray-scale sonography as a hypoechoic mass bulging on the fetal surface of the placenta in most cases. Calcification and necrosis are occasionally observed.…”

Récurrence de chorio-angiomes multiples : à propos d’un cas

“…Si le diagnostic anténatal de chorio-angiome est parfois aléatoire, le retentissement foetal (anasarque) peut guider l'attitude obstétricale. Toutefois, la dégradation peut être rapide, conduisant au décès dans un délai de moins d'une semaine notamment à la faveur de complications aiguës telles qu'une hémorragie intralésionnelle [10]. Face à cette évolution souvent imprévisible, certains auteurs préconisent une surveillance échographique au moins hebdomadaire puis journalière, le plus souvent en hospitalisation, lorsque le terme approche [26].…”

“…• de complications cardiovasculaires à titre d'insuffisance cardiaque [10]. Elles résultent de l'effet shunt gauchedroit des anastomoses artérioveineuses intratumorales et de l'hypoxie foetale chronique induite par l'insuffisance placentaire fonctionnelle ou l'anémie [4] ; • de complications hématologiques à titre d'anémie et de thrombopénie.…”