Rotational harvesting is one of the oldest management strategies applied to terrestrial and marine natural resources, with crop rotations dating back to the time of the Roman Empire. The efficacy of this strategy for sessile marine species is of considerable interest given that these resources are vital to underpin food security and maintain the social and economic wellbeing of small-scale and commercial fishers globally. We modeled the rotational zone strategy applied to the multispecies sea cucumber fishery in Australia's Great Barrier Reef Marine Park and show a substantial reduction in the risk of localized depletion, higher long-term yields, and improved economic performance. We evaluated the performance of rotation cycles of different length and show an improvement in biological and economic performance with increasing time between harvests up to 6 y. As sea cucumber fisheries throughout the world succumb to overexploitation driven by rising demand, there has been an increasing demand for robust assessments of fishery sustainability and a need to address local depletion concerns. Our results provide motivation for increased use of relatively low-information, low-cost, comanagement rotational harvest approaches in coastal and reef systems globally.T he sustainable management of natural resources is a fundamental challenge in the face of increasing human population and related demand for food, limited research and management capacity, and the drive for short-term economic development. Benthic organisms that are shallow and have limited motility can be particularly susceptible to overharvesting, especially, such as in the case of sea cucumbers, when they are comparatively valuable and easy to harvest and store and where communities rely on these resources for food and income (1, 2). The value and demand for sessile marine resources, such as sea cucumber, are rising (3), resulting in the general overexploitation and even high extinction risk for some sea cucumber populations globally (3, 4), even in seemingly well-managed fisheries, such as in the Great Barrier Reef Marine Park (GBRMP) (5, 6). Globally, there is a need to assess fishery sustainability to meet increasingly stringent requirements for ecological sustainability, particularly in regions with high conservation value. However, gathering and analyzing suitable fishery-dependent and -independent data are often beyond the financial and logistical capacities of the fishery, particularly for multispecies fisheries.In our study, we estimated the benefits of a rotational zone strategy (RZS) applied to the sea cucumber fishery of Australia's Great Barrier Reef (GBR) (Fig. 1), which has a 3-y rotation cycle through 154 zones. Under pressure from management over historical overexploitation of high-value species and a perceived high risk of overexploitation of other species, the fishers of the GBR sea cucumber fishery designed and implemented an RZS in 2004, where the entire GBR fishery area was split into 154 zones, with each zone fished only one time every 3 ...