Large-scale hot embossing

Worgull, Matthias; Heckele, M.; Schomburg, Werner Karl

doi:10.1007/s00542-005-0012-z

Cited by 63 publications

(40 citation statements)

References 5 publications

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“…Large-scale hot embossing to create low cost and high quality microfluidic structures has been presented [112]. Using simulation-based modifications, it is possible to improve the demolding forces and to reduce damage, such as shrinkage and warpage of microstructures during demolding.…”

Section: The Hot Embossing Techniquementioning

confidence: 99%

Polymer-Based Microfluidic Devices for Pharmacy, Biology and Tissue Engineering

2012

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This paper reviews microfluidic technologies with emphasis on applications in the fields of pharmacy, biology, and tissue engineering. Design and fabrication of microfluidic systems are discussed with respect to specific biological concerns, such as biocompatibility and cell viability. Recent applications and developments on genetic analysis, cell culture, cell manipulation, biosensors, pathogen detection systems, diagnostic devices, high-throughput screening and biomaterial synthesis for tissue engineering are presented. The pros and cons of materials like polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), polystyrene (PS), polycarbonate (PC), cyclic olefin copolymer (COC), glass, and silicon are discussed in terms of biocompatibility and fabrication aspects. Microfluidic devices are widely used in life sciences. Here, commercialization and research trends of microfluidics as new, easy to use, and cost-effective measurement tools at the cell/tissue level are critically reviewed.

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Section: The Hot Embossing Techniquementioning

confidence: 99%

Polymer-Based Microfluidic Devices for Pharmacy, Biology and Tissue Engineering

2012

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“…As part of a larger project to improve the micro embossing process Worgull et al [20] proposed reducing warpage and shrinkage of the moulded part using a frame to stop the flow front during moulding. Sacrificial features outside the functional area were proposed to protect the remaining features.…”

Section: Embossingmentioning

confidence: 99%

“…An auxiliary thermal stress barrier, similar to that proposed by Worgull et al [20], was proposed to protect the microstructures. In addition the use of Ni-PTFE as a mould material was recommended to achieve lower surface energy and friction force.…”

Section: Embossingmentioning

confidence: 99%

Demoulding Force Prediction for Micro Polymer Replication: A Review of Relevant Literature

Delaney¹,

Bissacco²,

Kennedy³

2010

Proceedings of the 7th International Conference on Multi-Material Micro Manufacture

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Demoulding components without damage to either the components or tool is critical to successful replication processes. During tooling development designers strive to optimize replication tools to minimize demoulding force and resultant stress on replicated parts. A critical element of this process is an accurate demoulding force prediction model. Various models have been proposed to predict demoulding forces, each showing limitations in its applicability. This paper reviews existing demoulding force models and parameters affecting demoulding force for micro polymer replication.

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“…That is why small structures should not be placed at the rim of a large film and the overall size of a patterned foil is limited. Up to now, the largest diameter on which micro structures have been made by hot embossing is 20 cm [3]. The cycle time of both injection molding and hot embossing is within the range of a few minutes, because the entire tool needs to be heated up and cooled down again.…”

Section: Introductionmentioning

confidence: 99%