Large-Scale Inhomogeneous Fluorescence Plasmonic Silver Chips: Origin and Mechanism

Plasmonic Gold Nanoisland Film for Bacterial Theranostics

“…Plasmonic nanomaterials have been extensively utilized for diagnostic applications because of their unique properties, such as a large surface area, easy surface modification, and distinct surface plasmon resonance [1][2][3][4][5][6][7][8][9][10]. Among various plasmonic nanomaterials, gold-based nanomaterials with tunable size and shape have been extensively applied for biomedical detection based on their optical and structural characteristics [11][12][13][14][15][16][17].…”

Monosaccharide-mediated rational synthesis of a universal plasmonic platform with broad spectral fluorescence enhancement for high-sensitivity cancer biomarker analysis

“…2 E), clarifying the necessity of irregular and inhomogeneous structural configurations for fluorescence enhancement in a broad spectrum. To elaborate upon the gap distance distribution, we applied skeletonization and computation to acquire Euclidean distances in a line segment [ 20 ] (Figs. 2 F and Additional file 1 : Fig.…”

“…The distance distribution of inhomogeneous gaps was quantified by gap skeletonization and computation of gap distances. Firstly, we categorized all image pixels into binary gaps (0) or silver structures (1) through the imbinarize function in MATLAB software R2020b with global thresholding computed using Otsu's method [ 20 ], followed by skeletonization and distance computation. Next, the ‘clean’ operation of the bwmorph function was performed, followed by the ‘majority’ operation to optimize final binary images.…”

“…Another emerging strategy replies on the near-field optical phenomenon named metal-enhanced fluorescence (MEF), where well-matched resonant fluorophores positioned in precisely-controlled proximity to nanoscopic plasmonic surfaces are augmented, as a combined result of enhanced local excitation of electric fields, dipolar coupling of surface plasmons to fluorescence emission, and increased radiative decay rates of excited-state fluorophores [ 8 , 9 ]. Since the introduction of the plasmonic resonance-controlled fluorescence [ 10 , 11 ], significant advances have been attained to amplify fluorescence, using noble metal nanoarchitectures including but not limited to periodically ordered arrays [ 12 – 14 ], colloidal NPs in a variety of geometric shapes [ 15 – 18 ], and nanoislands on glass substrate [ 19 , 20 ]. Given the warranted superiorities, MEF has been adopted with respect to clinical diagnosis for various ailments such as lung cancer [ 21 ], diabetes [ 22 ], cardiovascular diseases [ 23 ], and most recently, SARS-CoV-2 [ 24 ].…”

Simple but accurate estimation of light-matter coupling strength and optical loss for a molecular emitter coupled with photonic modes

“…Light-matter interaction plays a crucial role in various fields such as surface-enhanced Raman spectroscopy [1][2][3][4][5][6][7][8][9] , biosensing [10][11][12][13][14][15] , photosynthesis [16][17][18][19][20] , resonance energy transfer [21][22][23][24][25][26][27] , and molecular fluorescence [28][29][30][31][32][33][34][35][36] . Recently, due to advances in nanotechnology, the achievement of strong light-matter interaction [37][38][39][40][41] has motivated successive studies on the chemical properties of light-matter hybrid states, leading to the emergence of polariton chemistry [42][43][44][45][46] .…”