Large single cutaneous metastasis of colon adenocarcinoma mimicking a squamous cell carcinoma of the skin: A case report

Abstract

HighlightsSkin Cancer.Colorectal Cancer.Cutaneous Metastases.Fasciocutaneous Flaps.

Destination Unknown: A Unique Case of Metastatic Colorectal Carcinoma to the Breast, Axilla & Skin

“…It is usually thought to signify widely disseminated disease and generally a poorer prognosis, with patient survival documented to be an average of 18 months (1-34 months) [7]. Based on a small number of case reports of this entity, recommendations suggest that single cutaneous metastases should undergo wide excision with margins at least 1 cm, as was performed in this case.…”

Unusual Cutaneous Metastases From Colon Adenocarcinoma

“…Cutaneous metastases are relatively rare, mainly from internal malignancies, in which prevalence is about 1-4.3%, the most frequent sources being breast and lung cancers [1][2][3][4][5][6]. Their occurence usually reflects a widely disseminated disease, associated with poor prognosis, with an expected survival ranging from 1 to 34 months [1][2][3]9].…”

“…Although CRC is one of the most common cancers worldwide, cutaneous metastasis from this kind of internal tumour is extremely unusual, occurring in 4.2% of all colorectal malignancies [ 1 ]. They typically occur within the first two years after primary tumour resection and are often associated with simultaneous metastasis in other organs [ 1 - 3 , 6 , 9 ]. However, cutaneous metastases can be the first sign of CRC, although less frequently.…”

“…The skin is a relatively unusual site for internal tumour metastasis and remains a neglected, although relevant contributor, especially when total cancer incidence increases and more cancer survivors require surveillance for relapse [1]. Its prevalence stands around 1-4.3%, and major contributors from internal malignancies are breast and lung cancer, accounting for 32.7% and 13.2% of cases, respectively [1][2][3][4][5][6].…”

“…The more common sites of metastasis are the liver, lung and central nervous system. Cutaneous metastases from colorectal cancer are extremely rare (4.2%) and indicative of poor prognosis, reflecting the spread of disease [ 1 - 3 , 6 , 9 ]. The most frequent sites of cutaneous metastasis are incisional scars at the abdominal wall, scalp, face and neck [ 4 - 5 ].…”