Large Supratentorial Cortical Ependymoma in a Child

Yurt, Alaattin; Selçukı, Mehmet; Ertürk, Ali; Küpelioğlu, Ali

doi:10.3121/cmr.2010.877

Cited by 19 publications

(19 citation statements)

References 9 publications

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“…In the present series, the majority of the tumors were irregularly-lobulated, which was likely due to the fact that the tumors grew actively or the cell proliferation was not uniform. The tumors were hypointense to isointense relative to the gray matter on non-enhanced T1WI, and they were hyperintense or slightly hypointense on T2WI, similar to the appearances of other intracranial tumors (24). The architecture of the tumors in the present study was commonly heterogeneous, correlating with the MRI results and the microscopic findings; heterogeneous intensity can indicate various components of the lesion, such as cysts, necrosis, intratumoral hemorrhage, calcification, fibrosis or vascular proliferation (25).…”

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confidence: 70%

Magnetic resonance imaging findings of extraventricular anaplastic ependymoma: A report of 11 cases

et al. 2016

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Abstract. Anaplastic ependymomas are rare malignant tumors of the central nervous system. Few studies are available regarding their neuroradiological characteristics. The present study aimed to retrospectively review a series of patients with extraventricular anaplastic ependymoma and to analyze the magnetic resonance imaging (MRI) characteristics to distinguish anaplastic ependymoma from other intracranial tumors. The clinical and pathological images of 11 patients who presented with histologically proven anaplastic ependymoma at Nanfang Hospital (Southern Medical University, Guangzhou, Guangdong, China) between September 2004 and March 2015 were retrospectively reviewed. MRI scans were obtained in all 11 cases. Computed tomography scans were obtained in only 3 cases. In total, 8 tumors were located at the supratentorial parenchyma, and 3 tumors were derived from the cerebellar hemisphere. Images displayed quasi-circular (4/11), irregularly-lobulated (7/11) variable-intensity masses. The masses presented with cysts or necrosis (8/11), hemorrhage (7/11), marked (9/11) or mild (2/11) enhancement, and moderate (4/11), mild (3/11) or absent (4/11) peritumoral edema. The tumors were also frequently closely associated with the lateral ventricle (6/11). Tumors appeared isointense to hypointense on T1-weighted imaging (T1WI) and heterogeneously hyperintense or hypointense on T2WI, demonstrating wreath-like and ring-like characteristics, with intratumoral nodules (3/11) or marked flake-like inhomogeneous (6/11) enhancement on post-contrast MRI. Only 2 solid lesions showed mild enhancement (2/11). Although the MRI features of the extraventricular anaplastic ependymomas varied and were non-specific, these characteristic MRI findings, combined with the locations of the lesions, the age of onset and the short disease course, could be useful in differentiating anaplastic ependymomas from other intracranial neoplasms in the future.

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confidence: 70%

Magnetic resonance imaging findings of extraventricular anaplastic ependymoma: A report of 11 cases

et al. 2016

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“…GTR (10 of 14 patients in our series) is the optimal therapy for symptomatic supratentorial parenchymal ependymomas (2,3,(5)(6)(7)(8)(9)12,15,(18)(19)(20)(21)23). In the present series, the postoperative care of patients depended on the operative procedure.…”

Section: Treatment Proceduresmentioning

confidence: 86%

“…We did not recommend adjuvant therapy such as radiotherapy or chemotherapy if gross total surgical removal (GTR) had been achieved in the patients with low grade tumors (The WHO Grade I and Grade II ependymomas). The radiotherapy should only be given to patients with anaplastic ependymomas and tumors in locations where total excision is not possible (9,16,19,21).…”

Section: Surgical Proceduresmentioning

confidence: 99%

Supratentorial parenchymal ependymomas of children: experience with 14 patients at a single institute

Yin¹,

Li²,

Luo³

et al. 2015

Turkish Neurosurgery

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“…The clinical and pathological characteristics of supratentorial ependymomas in children are not well identified in the literature, because most series deal with ependymomas regardless of their location or age of the patient. Extraventricular ependymomas are especially rare, and while they have definite ependymal morphology, their histogenesis remains uncertain 10) . However, in some articles the pathogenesis of supratentorial, extraventricular, cortical, and ectopic ependymoma were explained in other ways.…”

Section: Discussionmentioning

confidence: 99%

“…The researchers concluded that post-operative radiotherapy did not play a role in treatment. However, in another recent study of supratentorial ependymomas, it has been suggested that radiotherapy should be given to patients with anaplastic ependymomas and in cases where only partial resection of either benign or malignant tumors has been achieved 10) . As mentioned previously, ependymomas can infiltrate surrounding normal tissue, so incomplete removal of the tumor during surgery may lead to a bad prognosis.…”

Section: Treatment and Prognosismentioning

confidence: 99%

Supratentorial Cortical Ependymoma in a 21-Month-Old Boy

Lee

Lim

Kim

2011

J Korean Neurosurg Soc

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Brain magnetic resonance (MR) revealed a 1.5×1.5 cm diffuse enhancing mass in the right postcentral gyrus cortex with some focal calcifications. magnetic resonance imaging (MRI) revealed hyperintensity on T1-weighted images and mixed hypo-to hypertensity on T2-weighted images. The mass had relatively smooth margins and only minimal brain swelling was noted around the peri-mass lesion. On the sagittal image the mass was closely contacted with dura of the sagittal sinus and falx. There was low signal line between the mass and dura, showing the presence of cerebro-spinal fluid. Imaging showed no evidence that the mass was connected to the ventricular ependymal lining (Fig. 1).The neuro-radiologic differential diagnosis included dysembryoplastic neuroepithelial tumor or low grade glioma, and meningioma less likely, due to the parasagittal tumor location. Operation and pathological findingsA right parietal craniotomy was performed and complete excision of the tumor was done. The tumor was firm, gray, and contained calcifications. It had well defined margins, allowing INTRODUCTIONEpendymomas are rare neuroectodermal tumors arising from ependymal cells of the ventricular system, choroid plexus, filum terminale, or central canal of the spinal cord. Ependymomas are relatively rare nervous system tumors, constituting 1.2% to 7.8% of all intracranial neoplasms or 2% to 6% of all gliomas 4,9) . Ependymomas are frequently infratentorial, and a third of ependymomas are supratentorial. Supratentorial ependymomas outside the ventricular system as a distinct location are infrequent. As reported in some articles, ectopic ependymoma can arise in the supratentorial parenchyma with no attachment to the ventricular system 3) . However, these are very rare and reported in only a few cases in the literature 9) . Our patient was only 21 months old, which to our knowledge, is the youngest pediatric case of supratentorial ectopic cortical ependymoma in published papers. Herein, the clinical features and pathologic findings of supratentorial ectopic cortical ependymoma in are described. CASE REPORT History and examinationA 21-month-old boy presented with repetitive left leg rigidity lasting two weeks. At birth he was delivered vaginally without J Korean Neurosurg Soc 50 : 244-247, 2011 http://dx.doi.org/10. 3340/jkns.2011.50.3.244 Copyright © 2011 The Korean Neurosurgical Society Two-thirds of ependymomas arise in the infratentorial or intraventricles, whereas one-third are located supratentorially. But supratentorial "cortical" ependymomas are very rare. We report a case of a cortical ependymoma in a 21-month-old boy. The patient presented with simple partial seizures. This tumor was located in the postcentral gyrus and he had gross total excision. Microscopy and immunohistochemistry showed grade II differentiation ependymoma.

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Large Supratentorial Cortical Ependymoma in a Child

Cited by 19 publications

References 9 publications

Magnetic resonance imaging findings of extraventricular anaplastic ependymoma: A report of 11 cases

Magnetic resonance imaging findings of extraventricular anaplastic ependymoma: A report of 11 cases

Supratentorial parenchymal ependymomas of children: experience with 14 patients at a single institute

Supratentorial Cortical Ependymoma in a 21-Month-Old Boy

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