Large Undifferentiated Pleomorphic Sarcoma of the Posterior Thigh

Allen, Austin H.

doi:10.12659/ajcr.914079

Cited by 11 publications

(11 citation statements)

References 11 publications

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“…About sarcomas retrospective studies determined that an adequate resection (wide margins) during treatment is the single most important prognostic factor for longterm survival as local relapse and distant metastases 10 .…”

Section: Discussionmentioning

confidence: 99%

Pleomorphic sarcoma of the jejunum: Case report

Nava-Lacorte¹,

Carreto-Navarrete²

2022

GAMO

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Small bowel tumors are rare and account for 1-2% of all gastrointestinal neoplasms and < 5% of all malignancies in the gastrointestinal tract. A 65-year-old man presented with anemia and melena for approximately 6 months, treated with several blood transfusions. Endoscopy is performed, finding gastritis atrophy. The patient underwent contrast computerized tomography identifying a tumor in jejunum proximal approximately 3 cm diameter, so laparotomy is performed finding tumor from 30 cm of Treitz angle, and it was performed resection with clear margins. Histological examination revealed pleomorphic sarcoma of jejunum.

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Section: Discussionmentioning

confidence: 99%

Pleomorphic sarcoma of the jejunum: Case report

Nava-Lacorte¹,

Carreto-Navarrete²

2022

GAMO

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“…These particular scans have the greatest sensitivity for high-grade sarcomas as the ability to differentiate between benign soft tissue tumors from lowor intermediate-grade sarcomas is limited [15–17]. If biopsy is performed, core needle biopsy is preferred due to its low incidence of complications and high diagnostic accuracy [18].…”

Section: Discussionmentioning

confidence: 99%

Spindle Cell Sarcoma of the Paraspinal Musculature with Late Pulmonary Metastases

Allen

Gullixson

2019

Am J Case Rep

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Patient: Male, 58 Final Diagnosis: Spindle cell sarcoma Symptoms: Chest wall tenderness • painful paraspinal mass • shortness of breath Medication: — Clinical Procedure: Surgical excision with chemotherapy and radiation Specialty: Oncology Objective: Rare disease Background: Sarcomas account for less than 1% of all cancers. Spindle cell sarcomas are a rare form of soft tissue sarcomas classified as undifferentiated/unclassified based on their histomorphology. These tumors have a propensity for local recurrence and distant metastases are frequently found in the lungs. The risk for metastases increases with higher-grade malignancy and the size of the primary tumor. The often-painless nature of these tumors results in a delay in diagnosis, and physicians frequently overlook sarcomas in their differentials due to their rarity, complicating the disease process. Case Report: This article reports a case of a spindle cell sarcoma in the left paraspinal musculature in a 58-year-old Caucasian male; the tumor was excised in large pieces. There was an initial benign course, during which time the patient was undergoing regular imaging studies to evaluate for recurrence. Eight years later, the tumor metastasized to the lungs with an initial presentation of shortness of breath and pleural effusion on imaging. Conclusions: Sarcomas are very rare soft tissue neoplasms, but they should not be overlooked in a physician’s differentials, especially when evaluating an enlarging mass. Recommended treatment of choice is complete surgical excision with adequate resection margins of at least 1 cm or greater to a fascial barrier. Recurrence and late pulmonary metastases are common and metastatectomy is the recommended treatment choice if metastases are present.

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“…We present a case of a large UPS in the right hamstring of a healthy 86-year-old male, initially evaluated with a bedside ultrasound and treated with surgical resection. We performed a review of the literature demonstrating this is one of the largest UPS that has been reported and successfully resected [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Use of Ultrasound for Evaluation of a Large Undifferentiated Pleomorphic Sarcoma in the Lower Extremity of an Elderly Male

Gencarelli¹,

Hali²,

Aurup³

2022

Cureus

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Soft tissue sarcomas arise infrequently and make up less than 1% of all cancers. An undifferentiated pleomorphic sarcoma (UPS), formerly known as a malignant fibrous histiocytoma, is a malignant subtype of soft tissue sarcoma identified by a lack of specific immunohistochemical markers for lineage differentiation. These tumors are aggressive and enlarge rapidly with an increased risk of metastasis, thus prompt diagnosis, treatment, and post-resection surveillance are imperative. This case report demonstrates an incidental finding of a large undifferentiated pleomorphic sarcoma of the posterior thigh in an 86-year-old male initially evaluated with a bedside ultrasound.

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Large Undifferentiated Pleomorphic Sarcoma of the Posterior Thigh

Cited by 11 publications

References 11 publications

Pleomorphic sarcoma of the jejunum: Case report

Pleomorphic sarcoma of the jejunum: Case report

Spindle Cell Sarcoma of the Paraspinal Musculature with Late Pulmonary Metastases

Use of Ultrasound for Evaluation of a Large Undifferentiated Pleomorphic Sarcoma in the Lower Extremity of an Elderly Male

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