Large volume injection in capillary GC using PTV injectors: Comparison of inertness of packing materials

Abstract

DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers. Link to publication General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. • Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal. If the publication is distributed under the terms of Article 25fa of the Dutch Copyright Act, indicated by the "Taverne" license above, please follow below link for the End User Agreement:

Optimization of large-volume programmed-temperature vaporizing injection for gas chromatography—Mass spectrometry. Analysis of narcotics and stimulants in biological fluids with reduced sample consumption

“…Adsorbent-packed injector inserts could be used to avoid or minimize losses of volatile analytes during solvent venting. Tenax-TA, a commonly used adsorbent in PTV injection [12,13], was tested as packing material, but the higher boiling analytes (except amphetamine and methamphetamine) could not be transferred efficiently during the desorption step. Consequently, glass wool-packed injector inserts were used for further investigations.…”

Large volume splitless injection with concurrent solvent recondensation: Keeping the sample in place in the hot vaporizing chamber

“…The laminar liner shows better chromatographic performance [21], but does not reliably arrest 20 -50 lL of sample liquid. This dilemma is not new: deactivated glass or fused silica wool performs perfectly for the injection of non-adsorptive, stable compounds, but insufficient inertness has been described for conventional splitless injection [23] as well as for programmed temperature vaporizing injection (PTV) [24,25].…”

Trace level analysis of micropollutants in aqueous samples using gas chromatography with on-line sample enrichment and large volume injection

“…Recently, Mol et al proposed an alternative method for PTV-based large volume sampling in capillary GC [48,49]. By applying liners with a much larger inner diameter (3.5 mm instead of the usual 1 mm) the volume of liquid sample that can be retained in a packed insert was increased to ca.…”