Larval Environmental Temperature and the Susceptibility of<i>Aedes albopictus</i>Skuse (Diptera: Culicidae) to Chikungunya Virus

Westbrook, Catherine J.; Reiskind, Michael H.; Pesko, Kendra N.; Greene, Krystle; Lounibos, L. Phillip

doi:10.1089/vbz.2009.0035

Cited by 135 publications

(139 citation statements)

References 46 publications

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“…albopictus DENV-1 infection, although these effects do not appear to alter rates of vertical transmission, which indicate a unique reproductive barrier(s) to transmission. These results are consistent with Westbrook et al (2010), who showed that Ae. albopictus reared at a cooler larval temperature (18 C) had higher chikungunya virus infection and dissemination rates compared with those reared at a warmer larval temperature (32 C).…”

Section: Discussionsupporting

confidence: 93%

Larval Temperature–Food Effects on Adult Mosquito Infection and Vertical Transmission of Dengue-1 Virus

2015

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Temperature-food interactions in the larval environment can affect life history and population growth of container mosquitoes Aedes aegypti (L.) and Aedes albopictus Skuse, the primary vectors of chikungunya and dengue viruses. We used Ae. aegypti, Ae. albopictus, and dengue-1 virus (DENV-1) from Florida to investigate whether larval rearing temperature can alter the effects of larval food levels on Ae. aegypti and Ae. albopictus life history and DENV-1 infection and vertical transmission. Although we found no effect of larval treatments on survivorship to adulthood, DENV-1 titer, or DENV-1 vertical transmission, rates of vertical transmission up to 16-24% were observed in Ae. albopictus and Ae. aegypti, which may contribute to maintenance of this virus in nature. Larval treatments had no effect on number of progeny and DENV-1 infection in Ae. aegypti, but the interaction between temperature and food affected number of progeny and DENV-1 infection of the female Ae. albopictus parent. The cooler temperature (24 C) yielded the most progeny and this effect was accentuated by high food relative to the other conditions. Low and high food led to the highest ($90%) and lowest ($65%) parental infection at the cooler temperature, respectively, whereas intermediate infection rates ($75-80%) were observed for all food conditions at the elevated temperature. These results suggest that temperature and food availability have minimal influence on rate of vertical transmission and a stronger influence on adults of Ae. albopictus than of Ae. aegypti, which could have consequences for dengue virus epidemiology.

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Section: Discussionsupporting

confidence: 93%

Larval Temperature–Food Effects on Adult Mosquito Infection and Vertical Transmission of Dengue-1 Virus

2015

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“…Our model assumes that all parameters are independent. However, it is likely that some are correlated; for instance temperature may simultaneously influence vector competence, biting rate, and vector life history [51,52]. To our knowledge, there have been no lab or field studies examining the effects of temperature on Zika replication in mosquitoes and there is very little on the affect of temperature on chikungunya's EIP [9, 52,53].…”

Section: Discussionmentioning

confidence: 99%

Defining the risk of Zika and chikungunya virus transmission in human population centers of the eastern United States

Manore

Ostfeld

Agusto

et al. 2016

Preprint

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The recent spread of mosquito-transmitted viruses and associated disease to the Americas motivates a new, data-driven evaluation of risk in temperate population centers. Temperate regions are generally expected to pose low risk for significant mosquito-borne disease; however, the spread of the Asian tiger mosquito (Aedes albopictus) across densely populated urban areas has established a new landscape of risk. We use a model informed by field data to assess the conditions likely to facilitate local transmission of chikungunya and Zika viruses from an infected traveler to Ae. albopictus and then to other humans in USA cities with variable human densities and seasonality. Mosquito-borne disease occurs when specific combinations of conditions maximize virus-to-mosquito and mosquito-to-human contact rates. We develop a mathematical model that captures the epidemiology and is informed by current data on vector ecology from urban sites. The model demonstrates that under specific but realistic conditions, fifty-percent of introductions by infectious travelers to a high human, high mosquito density city could initiate local transmission and 10% of the introductions could result in 100 or more people infected. Despite the propensity for Ae. albopictus to bite non-human vertebrates, we also demonstrate that local virus transmission and human outbreaks may occur when vectors feed from humans even just 40% of the time. Inclusion of human behavioral changes and mitigations were not incorporated into the models and would likely reduce predicted infections. This work demonstrates how a conditional series of non-average events can result in local arbovirus transmission and outbreaks of human disease, even in temperate cities.

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“…Sindbis virus infection and dissemination rates have been found to be higher in Ae. aegypti mosquitoes after rearing larvae at higher temperatures [80], whereas, in contrast, studies have shown increased CHIKV (and YF) infection rates in larvae raised at lower temperatures [71,72].…”

Section: The Role Of Climate In Insect Vector-pathogen Interactionsmentioning

confidence: 91%

“…aegypti [71] and Ae. albopictus [72]. Dengue virus (DENV) infection rates are also temperature-dependent, demonstrating increased infection and transmission rates at higher temperatures [73][74][75][76], as well as altered infection rates and EIP in response to fluctuating temperatures and diurnal temperature range (DTR).…”

Section: The Role Of Climate In Insect Vector-pathogen Interactionsmentioning

confidence: 99%

Climate, environmental and socio-economic change: weighing up the balance in vector-borne disease transmission

Parham

Waldock

Christophides

et al. 2015

Phil. Trans. R. Soc. B

246

224

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Arguably one of the most important effects of climate change is the potential impact on human health. While this is likely to take many forms, the implications for future transmission of vector-borne diseases (VBDs), given their ongoing contribution to global disease burden, are both extremely important and highly uncertain. In part, this is owing not only to data limitations and methodological challenges when integrating climate-driven VBD models and climate change projections, but also, perhaps most crucially, to the multitude of epidemiological, ecological and socio-economic factors that drive VBD transmission, and this complexity has generated considerable debate over the past 10–15 years. In this review, we seek to elucidate current knowledge around this topic, identify key themes and uncertainties, evaluate ongoing challenges and open research questions and, crucially, offer some solutions for the field. Although many of these challenges are ubiquitous across multiple VBDs, more specific issues also arise in different vector–pathogen systems.

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Larval Environmental Temperature and the Susceptibility ofAedes albopictusSkuse (Diptera: Culicidae) to Chikungunya Virus

Cited by 135 publications

References 46 publications

Larval Temperature–Food Effects on Adult Mosquito Infection and Vertical Transmission of Dengue-1 Virus

Larval Temperature–Food Effects on Adult Mosquito Infection and Vertical Transmission of Dengue-1 Virus

Defining the risk of Zika and chikungunya virus transmission in human population centers of the eastern United States

Climate, environmental and socio-economic change: weighing up the balance in vector-borne disease transmission

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