Larvaterapia aplicada a heridas con poca carga de tejido necrótico y caracterización enzimática de la excreción secreción y hemolinfa

Téllez, Germán Alberto; Acero, Mónica Alejandra; Pineda, Luz Adriana; Castaño, Jhon Carlos

doi:10.7705/biomedica.v32i3.669

Cited by 6 publications

(3 citation statements)

References 22 publications

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“…13,14 Several studies, either in the form of a clinical trial or as a systematic review, have examined the effect of larval treatment on different patients group and different aspects. [15][16][17] Valachová et al, in their study, showed that larval treatment is more effective than conventional treatments in debridement of chronic ulcers that is consistent with the results of our study. Lepage et al, in their clinical trial study, investigated the effect of larval treatment in comparison with hydrogel in wound healing and increasing of quality-adjusted life years (QALYs), which did not show any difference between the two groups.…”

Section: Discussionsupporting

confidence: 93%

Effects of Lucilia sericata Maggot Therapy in Chronic Wound Treatment: A Randomized Clinical Trial

Ehsan¹,

Hasani²,

Zolfaghari³

et al. 2020

CWCMR

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Background: Chronic ulcers are one of the challenges of treatment today and cost a lot to the health system. The present study was conducted to investigate the effect of Lucilia sericata maggot therapy in chronic wound treatment. Materials and Methods: This study was conducted as a clinical trial study with 90 eligible patients. Patients were randomly assigned to two equal intervention and control groups. Both groups received routine treatments for chronic ulcers. Patients in the intervention group received maggot therapy with larvae of Lucilia sericata. For all patients, a smear and culture of wound discharges were acquired. The condition of wound healing, the type of infection, and the reduction of microorganisms were compared between the two groups. Results: Staphylococcus aureus was present in 68.9% of the patients and was the most abundant infection among all patients. Results of culturing after larval treatment at different times revealed a decrease in the number of all bacteria, especially Pseudomonas aeruginosa, Escherichia coli, and S. aureus, but the response rate for Enterococcus was the lowest. Also, the wound healing rate and reduction in necrotic tissue at the end of the second week (p=0.041) and the third week (p=0.012) was significantly higher in the intervention group. Conclusion: Larvae of L. sericata have the highest effects on P. aeruginosa and had the least effect on the growth of Enterococcus. Also, our results showed larvae of L. sericata therapy can significantly improve wound healing rate.

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Section: Discussionsupporting

confidence: 93%

Effects of Lucilia sericata Maggot Therapy in Chronic Wound Treatment: A Randomized Clinical Trial

Ehsan¹,

Hasani²,

Zolfaghari³

et al. 2020

CWCMR

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“…Several of the factors that affect the healing process of ulcers and wounds are humidity, pressure, infection, necrotic tissue, and age, nutritional status and concomitant diseases of the patient [4]. The mechanism of skin repair is induced by an injury that alters the skin surface.…”

Section: Introductionmentioning

confidence: 99%

Characterization and efficacy of chitosan membranes in the treatment of skin ulcers

López‐Cervantes

Escárcega-Galaz

Sánchez‐Machado

et al. 2019

Egyptian Journal of Basic and Applied Sciences

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Chronic wounds aggravate the patient's indisposition by causing mobility, economic and social problems. Chitosan is a natural polymer that is considered a potent healing agent for skin lesions and has been used previously to manufacture dressings for wounds. The aim of this work was to evaluate the curative effect of chitosan membranes on cutaneous ulcers. The chitosan was characterized by measuring the degree of deacetylation and FTIR. The membranes were obtained by a solvent evaporation technique. Four patients with cutaneous ulcers were recruited to evaluate the effectiveness of the topical membranes. At the beginning of the in vivo assay, patients presented with infected wounds. By the end of treatment, the infection subsided, the granulation process was promoted and complete skin coverage was observed in most patients. The use of chitosan as a treatment for the healing of skin ulcers is considered highly promising for its medicinal properties, as well as for its affordability compared to traditional treatments.

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“…Atualmente, milhares de pacientes comúlceras de difícil cicatrização de diferentes etiologias, vêm sendo tratados com terapia larval como nos Estados Unidos, Austrália, Israel e em vários países da Europa [Ferraz et al 2014]. A Terapia Larval (TL) consiste na utilização de formas imaturas de moscas desinfectadas para a limpeza e remoção de tecidos desvitalizados em feridas, tais como:úlceras de pé diabético,úlceras póscirúrgicas infectadas,úlceras de decúbito,úlceras por estase venosa e em queimaduras [Téllez et al 2012].…”

Section: Introductionunclassified

Segmentação Semi-Automática de Úlceras para Terapia Larval

Marques¹,

Carvalho²,

Silva³

et al. 2017

Anais Do Simpósio Brasileiro De Computação Aplicada À Saúde (SBCAS)

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A Terapia Larval (TL) é um método alternativo para o tratamento deúlceras de difícil cicatrização. Ela utiliza formas imaturas de moscas para a limpeza dessas feridas, diminuindo a necessidade de amputações. Um uso mais eficiente da TL considera aárea da ferida. Para este cálculo geralmente são usadas técnicas invasivas como a planimetria manual com filme plástico. Investigamos uma técnica alternativa para orientar a TL com o uso da análise de imagens de feridas. Este trabalho investiga o uso do algoritmo Watershed para segmentação semi-automática deúlceras que serão submetidas a TL.

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Larvaterapia aplicada a heridas con poca carga de tejido necrótico y caracterización enzimática de la excreción secreción y hemolinfa

Cited by 6 publications

References 22 publications

<p>Effects of<em> Lucilia sericata</em> Maggot Therapy in Chronic Wound Treatment: A Randomized Clinical Trial</p>

<p>Effects of<em> Lucilia sericata</em> Maggot Therapy in Chronic Wound Treatment: A Randomized Clinical Trial</p>

Characterization and efficacy of chitosan membranes in the treatment of skin ulcers

Segmentação Semi-Automática de Úlceras para Terapia Larval

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