Larvicidal activity of two seaweeds, Enteromorpha flexuosa J. Agardh and Gracilara corticata J. Agardh Against Mosquito Vector, Anopheles stephensi

Poonguzhali, T. V.; Josmin, L L; Nisha, Laali

doi:10.13005/bbra/1131

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…The larvicidal potential of plant metabolites have been documented by several researchers. 23,[27][28][29][30] None has reported the larvicidal potential of extracts and fractions of the rhizomes of Aristolochia albida. Therefore, to the best of our knowledge, this study represents the first report of the larvicidal potential of the chloroform, methanol and aqueous extract of Aristolochia albida on Culex quinquefasciatus.…”

Section: Resultsmentioning

confidence: 99%

Larvicidal Assessment of Fractions of Aristolochia albida Rhizome on Culex quinquefasciatus

Usman¹,

Sallau²,

Salihu³

et al. 2018

TJNPR

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Aristolochia albida is a plant, native of Africa that has found various applications including antiparasite and anti-snake venom. In the present study, Aristolochia albida rhizome was extracted successively with chloroform and methanol by maceration technique. The extracts were tested for their larvicidal activity against 3 rd and 4 th instar larvae of Culex quinquefasciatus mosquito, according to WHO guidelines for larvicidal bioassay, with slight modifications. Fractionation of the chloroform extract was carried out using column chromatography. Larvicidal bioassay was carried out on the fractions obtained and the most potent fraction (fraction S) was further analyzed using preparative Thin Layer Chromatography (TLC) and characterized using Gas Chromatography-Mass Spectrometry (GC-MS) and Fourier Transform Infra-Red (FTIR) spectroscopic analyses. Chloroform extract showed the highest mortality (100%) at 25 ppm, with LC50 and LC90 values of 4.24 ppm and 7.59 ppm. Fractionation of the chloroform extract of Aristolochia albida rhizome yielded 180 fractions. Fraction S was the most potent fraction having the lowest LC50 value (1.12 ppm). Preparative TLC profile of fraction S yielded five distinct spots (S1-S1a, S2-S2a and S3). Assessment of the larvicidal activity of the fractions confirmed that they act in a synergistic manner. Likely compounds identified using GC-MS were columbin, benzene acetaldehyde, oleic acid, naphthalene and fucosterol. FTIR analysis identified some functionalities, such as, alcohols, aromatics and carboxylic acids. It was concluded from the present study that chloroform extract and fractions of Aristolochia albida possess larvicidal activity against Culex quinquefasciatus.

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Section: Resultsmentioning

confidence: 99%

Larvicidal Assessment of Fractions of Aristolochia albida Rhizome on Culex quinquefasciatus

Usman¹,

Sallau²,

Salihu³

et al. 2018

TJNPR

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An Overview of Indian Marine Seaweeds and their Medicinal Applications

R.,

Ananthy,

Salwe

et al. 2024

Journal of Pharmacology and Pharmacotherapeutics

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Background Seaweeds are macroalgae containing bioactive compounds that have positively impacted the biomedical field due to polysaccharides, sterols and glycolipids, showing a diverse range of pharmacological and biological properties. Eating a diet high in marine items will lessen the risk of developing diabetes, cancer and obesity. Purpose The exploration of medically useful seaweeds is required to identify drugs and drug targets and reduce the risk of developing diseases. Methods The PubMed search was done with the MESH terms such as seaweed and Marine algae pharmacological activity results were obtained as 748 results. We filtered out the articles and entered key terms related to our area of interest to find the results. The seaweed species in India are listed with Tamil Nadu contributing the most and Orissa the least. The type of algae is also mentioned. Results Marine algae have been employed in industry and medicine as a novel food with possible nutritional benefits. Furthermore, it has been demonstrated that marine algae are a rich source of naturally occurring bioactive substances with activities such as anti-diabetic, hepatoprotective, antiviral, antifungal, antibacterial, antimicrobial, antioxidant, anti-inflammatory, anti-hypercholesterolemia and hypolipidemia. Conclusion The current review focuses on the bioactivities and potential pharmaceutical activity of marine algae discovered in India. The present review article showed that there are many seaweeds of medical importance, and it is necessary to explore them to minimize disease progression and prolong the individual’s survival.

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Larvicidal activity of two seaweeds, Enteromorpha flexuosa J. Agardh and Gracilara corticata J. Agardh Against Mosquito Vector, Anopheles stephensi

Cited by 2 publications

References 10 publications

Larvicidal Assessment of Fractions of Aristolochia albida Rhizome on Culex quinquefasciatus

Larvicidal Assessment of Fractions of Aristolochia albida Rhizome on Culex quinquefasciatus

An Overview of Indian Marine Seaweeds and their Medicinal Applications

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