Larvicidal efficacy of nitenpyram on the treatment of myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in dogs

Abstract

The purpose of our study was to evaluate the larvicidal efficacy of nitenpyram for the treatment of screwworm myiasis caused by Cochliomyia hominivorax in naturally infested dogs. Seven Beagle dogs presenting with myiasis were treated with nitenpyram twice at an interval of 6 h. The animals received dosages between 1.43 and 4.42 mg/kg body weight of nitenpyram in each given treatment. The criteria used to determine the drug efficacy were larval expulsion and fall. These were quantified at 15 min intervals within the first hour followed by 2, 3, 4, 6, and 18 h post-treatment. The highest larval expulsion happened between 1 and 2 h post-treatment. The spontaneous larval expulsion percentages were 86% and 94.11% for 6 and 18 h after the first treatment, respectively. Larvae were expelled until 18 h post-treatment. After this period the remaining dead larvae were mechanically removed. Nitenpyram showed 100% efficacy on the treatment of myiasis by C. hominivorax in naturally infested dogs.

Toxic effects of nitenpyram on antioxidant enzyme system and DNA in zebrafish (Danio rerio) livers

“…When external contaminants enter the organism, these superoxide anions and oxygen free radicals, namely ROS, will be produced (Rana and Shivanandappa, 2010). Nitenpyram can be absorbed fast by blood and then caused the host death by interfering nervous transmissions (Correia et al, 2010). In the present assay, the ROS levels significantly increased with exposure to high concentration treatment.…”

Os parasitas de ovinos

“…Neste caso, o uso de inseticidas é indispensável. Entre os antiparasitários utilizados para a prevenção/controle da bicheira está a doramectina Muniz et al, 1995a;Muniz et al, 1995b;Sanavria et al, 1996;Caproni Jr et al, 1998;Anziani et al, 2000), ivermectina (Benitez et al, 1997), fipronil (Lima et al, 2004), dicyclanil (Anziani et al, 1998), nitenpyram (Correia et al, 2010) e também os organofosforados coumaphos, ronnel, chlorpyrifos, chlorfenvinfos e trichlorfon . Muitas vezes, faz-se necessária a aplicação de antibióticos sistêmicos para evitar a ocorrência de infecções bacterianas secundárias, o que também facilita a cicatrização.…”

Traumatic myiasis in free-ranging eland, reported from Kenya

“…Rejoining a herd after treatment is therefore suggestive that the individual has recovered and has regained fitness. Ivermectin and doramectin are among the common larvicidal agents [18,19], giving up to 100% efficacy in the treatment of myiasis in domesticated animals [20]. In the present case, we suggest that our treatment regime, which was based on Ivermectin, was effective on these wild elands.…”