Larvicidal, leishmanicidal, insecticidal and anthelmintic effects of Sterculia diversifolia stem bark and leaf

Rabbi, Fazle; Zada, Amir; Nisar, Amna

doi:10.3329/bjp.v15i1.43235

Cited by 10 publications

(3 citation statements)

References 22 publications

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“…There is information about the possible mechanism of action of some phenolic compounds on the eggs or larvae of gastrointestinal nematodes. The anthelmintic activity of phenolic compounds could be associated with the enzymatic process of parasites; the exchange of these compounds with the H. contortus eggshell structures could provoke inhibition of the development of the eggs to the following stage ( Rabbi et al, 2020 ; Ondua et al, 2021 ). The interaction of some phenolic compounds with the egg membrane causes structural changes affecting its permeability, oxygen exchange, and release of substances and enzymes involved in eggshell degradation and this allows no release of the larvae ( Rogers & Brooks, 1977 ; Vargas-Magaña et al, 2014 ; Engström et al, 2016 ).…”

Section: Discussionmentioning

confidence: 99%

Bioactive compounds from the parasitic plant Arceuthobium vaginatum inhibit Haemonchus contortus egg hatching

Becerril-Gil,

Estrada-Flores,

González-Cortazar

et al. 2024

Rev. Bras. Parasitol. Vet.

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The aim of this study was to assess the in vitro ovicidal activity of an ethyl acetate extract from Arceuthobium vaginatum (EtOAc-E) and their subfractions (AvR5-AvR14) against Haemonchus contortus using the egg hatching inhibition (EHI) test. The EtOAc-E and subfractions were tested at 0.12-2.00 and at 0.015-2.0 mg/mL, respectively. Distilled water and methanol (2%) were used as negative controls and Thiabendazole (0.10 mg/mL) as a positive control. Treatments with a dependent effect on concentration were subjected to regression analysis to determine the effective concentrations (EC50 and EC90). The major secondary compounds present in the extract and subfractions were identified by high performance liquid chromatography (HPLC). The EtOAc-E and AvR9 exhibited the best ovicidal effect recording 97.5 and 100% of EHI at 0.25 mg/mL, respectively. The EtOAc-E and AvR9 displayed an EC50= 0.12 and 0.08 mg/mL, respectively. The HPLC analysis in the EtOAc-E and bioactive fractions indicated the presence of a polyphenol, glycosylated flavanones, quercetin glucoside, cinnamates, coumarin, cinnamic acid derivative, ferulic acid, coumarate, naringenin, protocatechuic acid and naringin. Results demonstrated that A. vaginatum extract and fraction is able to inhibit the egg hatch process of H. contortus and could be a viable option for the control of small ruminant haemonchosis.

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Section: Discussionmentioning

confidence: 99%

Bioactive compounds from the parasitic plant Arceuthobium vaginatum inhibit Haemonchus contortus egg hatching

Becerril-Gil,

Estrada-Flores,

González-Cortazar

et al. 2024

Rev. Bras. Parasitol. Vet.

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“…A specimen has been placed in the botany department's herbarium by affixing a numbered voucher (Bot.20964, PUP), after getting identification from the competent specialist. The plant was ground with a grinder into powder form, after shade drying [23,24].…”

Section: Plant Collection and Taxonomic Identificationmentioning

confidence: 99%

Bio‐fabrication of silver nanoparticles using an aqueous extract of Quercus baloot: Preparation, characterization and in vitro antimicrobial evaluation

Rabbi,

Nisar,

Nawaz

et al. 2023

Micro & Nano Letters

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In the current study, a novel method was used to synthesize silver nanoparticles (AgNPs) by utilizing Quercus baloot aqueous extract as a reducing agent. The biosynthesized AgNPs were then subjected to various physicochemical characterizations to assess their effectiveness against microbial familiarity. The characterization techniques included ultraviolet‐visible spectro‐photometry (UV‐Vis), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X‐ray diffractometer (XRD), and Fourier‐transform infrared spectroscopy (FTIR). The UV‐Vis analysis revealed a distinctive spectral peak at 420 nm, indicating the presence of silver nanoparticles. SEM imaging displayed the nanoparticle size range of about 100 nm at a magnification of 30,000x, while TEM demonstrated that the nanoparticles had a spherical morphology with a size of approximately 100 nm. Moreover, the crystalline structure of the silver nanoparticles was confirmed by XRD analysis, further validating their successful synthesis. Additionally, FTIR analysis provided evidence of the presence of phytochemicals involved in synthesizing the AgNPs. the biosynthesized silver nanoparticles (AgNPs) were evaluated for antibacterial and antifungal activities. The AgNPs displayed substantial efficacy against common bacterial strains, including Staphylococcus aureus (71%), Escherichia coli (59%), and Klebsiella pneumoniae (64%). Furthermore, they demonstrated significant antifungal activity against plant pathogenic fungi, namely Aspergillus niger (65%), Aspergillus flavus (70%) and Fusarium oxysporum (61%).

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“…These three compounds were purified using thin layer chromatography followed by treating with ceric sulphate and then heated. The structures of isolated compounds were elucidated using UV, IR, 1 H-NMR, 13 C-NMR and 2D-NMR analytical techniques (Rabbi et al, 2020a, Rabbi et al, 2020c.…”

Section: Isolation and Characterizationmentioning

confidence: 99%

Evaluation of in-Vivo Biological Activities of Sterculia Diversifolia (G. Don) in Relevance to the Isolated Secondary Metabolites

2020

THE JAPS

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Genus Sterculia possess various types of compounds which have therapeutic potential. This study was aimed to explore the anticonvulsant, CNS depressant, analgesic, anti-inflammatory and anti-pyretic activities of Sterculia diversifolia stem bark and leaves extracts in mice. The secondary metabolites in MESD (methanolic extract of Sterculia diversifolia) was characterized by UV, IR, 1 H-NMR, 13 C NMR and 2D-NMR spectra in combination with EI-MS spectrometric techniques. Anticonvulsant and CNS depressant effect of MESD was assessed using strychnine-induced convulsion and phenobarbitone-induced hypnotic protocol. Analgesic activity was performed by acetic acid induced writhing and hot plate test while anti-inflammatory and anti-pyretic activities were assessed by carrageenan induced right hind paw edema and brewer's yeast induced pyrexia. The isolation of compounds with different elucidation techniques (1 H-NMR, 13 C NMR and 2D-NMR spectra in combination with EI-MS spectrometric techniques) led to luteolin, isoquercitrin and ursolic acid. The current study results showed that crude MESD significantly (p < 0.05) delayed the onset, shortened the duration and offered protection against strychnine-induced convulsion. Crude MESD significantly (p < 0.05) prolonged the time of phenobarbitone-induced hypnosis. The analgesic response of crude MESD stem bark was more significant as compare to crude MESD leaves, while crude MESD also showed significant anti-inflammatory and antipyretic activity through dose dependent phenomenon. These significant results might be due to flavonoids (luteolin, isoquercitrin) and triterpenoids (ursolic acid) presence, though the involvement of other biologically active secondary metabolites cannot be overlooked.

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Larvicidal, leishmanicidal, insecticidal and anthelmintic effects of Sterculia diversifolia stem bark and leaf

Cited by 10 publications

References 22 publications

Bioactive compounds from the parasitic plant Arceuthobium vaginatum inhibit Haemonchus contortus egg hatching

Bioactive compounds from the parasitic plant Arceuthobium vaginatum inhibit Haemonchus contortus egg hatching

Bio‐fabrication of silver nanoparticles using an aqueous extract of Quercus baloot: Preparation, characterization and in vitro antimicrobial evaluation

Evaluation of in-Vivo Biological Activities of Sterculia Diversifolia (G. Don) in Relevance to the Isolated Secondary Metabolites

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