Laryngeal blastomycosis with subsequent heart failure from itraconazole therapy

Tsang, Daniel; Haddad, Sara; Sternlieb, Mitchell

doi:10.1016/j.idcr.2022.e01463

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2024

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Cited by 6 publications

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“…Therefore, there is an urgent need to improve the drug release and absorption with an aim to lower the drug's side effect for causing heart failure. [29][30][31] To solve this problem, the M-Silica xerogel was used as an ITZ carrier and the loaded waterinsoluble drug was found to be amorphous in the M-Silica xerogel, and the entrapped micelles exerted certain functions to avoid drug re-crystallization in the system. Furthermore, the characteristics of the M-Silica xerogel as well as its drug-release management principles were systemically investigated, which could give a strong foundation for the further study of silica xerogel drug-delivery systems.…”

Section: Introductionmentioning

confidence: 99%