Laryngeal carcinoma in black patients

Abstract

The majority of reports on laryngeal carcinoma are from institutions serving a mostly white population. This report is about laryngeal carcinoma in black patients at Harlem Hospital Center. In a retrospective analysis, 113 patients (male-female, 3.5:1) with carcinoma of the larynx were examined. Sixty-seven patients (59%) were between 50 and 60 years of age. There were two patients (2%) with carcinoma in situ, 15 (13%) in Stage I, 40 (35%) in Stage II, 39 (35%) in Stage III, and 15 (13%) in Stage IV. Of the 113 patients, 70 (62%) were treated surgically, Group I; 24 (21%) received radiotherapy only, Group 2; and 19 (17%) refused treatment or died before therapy initiation. For patients in Group 1, the 1-year survival rate was 68% (43 of 63), the 3-year survival rate was 38% (20 of 53), and the 5-year survival rate was 15% (7 of 47). For Group 2, the survival rate was 48% (11 of 23), 30% (7 of 23), and 14% (3 of 22), respectively. In this patient population, laryngeal carcinoma occurred at a younger age than other reported groups, had a higher incidence in females, and had a lower 1-, 3-, and 5-year survival rate.

T1 glottic carcinoma involving the posterior commissure

“…Laryngeal carcinoma accounts for 30% to 50% of all head and neck cancers1–3 and about 1% of all newly diagnosed cancers in the United States 1, 4. The incidence is four times higher in men than women 4, 5. Smoking is associated in 95% of all laryngeal malignancies,6–9 and poses a significant risk factor for glottic carcinoma in women.…”

The Changing Demographics of Head and Neck Squamous Cell Carcinoma in the United States

“…The incidence of HNSCCA also varies according to race, with black patients having a higher incidence at most upper aerodigestive tract sites than white patients. 4 Although little is known about the incidence of HNSCCA in racial and ethnic groups other than groups of black and white patients in the United States, migration and other demographic trends have led to a great increase in the foreign-born population, particularly in the number of Asian and Hispanic individuals and individuals of other minority groups. 5 Such trends suggest that the number of individuals belonging to minority groups in the HNSCCA patient population is likely to grow, particularly the number of Asian and Hispanic individuals.…”

Healthcare Disparities in Laryngology: A Scoping Review

“…17,43,53 Higher incidence in females (22%) in predominantly AA cohort vs. other reported groups. 53 (Continues) Sex/gender Advanced disease: surgery patients more likely male and/or women more likely to undergo CRT/RT. 42,51 Inferior survival in males.…”