Laryngeal Manifestations of Rheumatoid Arthritis

Hamdan, Abdul‐Latif; Sarieddine, Doja

doi:10.1155/2013/103081

Cited by 38 publications

(37 citation statements)

References 43 publications

(44 reference statements)

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“…9) Other symptoms may include laryngeal mucosal edema, myositis of the intrinsic laryngeal muscles, inflammatory masses or rheumatoid nodules, and bamboo nodes. 6) The clinical presentation of laryngeal rheumatoid nodules vary from being asymptomatic to causing life-threatening respiratory symptoms and include sore throat, cough, foreign body sensation, odynophagia, hoarseness, dysphonia, change in voice quality, and respiratory distress. 5,6) The previous papers published in Korea have reported only two cases of vocal cord paralysis with cricoarytenoid joint fixation caused by rheumatoid arthritis.…”

Section: Discussionmentioning

confidence: 99%

“…6) The clinical presentation of laryngeal rheumatoid nodules vary from being asymptomatic to causing life-threatening respiratory symptoms and include sore throat, cough, foreign body sensation, odynophagia, hoarseness, dysphonia, change in voice quality, and respiratory distress. 5,6) The previous papers published in Korea have reported only two cases of vocal cord paralysis with cricoarytenoid joint fixation caused by rheumatoid arthritis. 4,11) To the best of our knowledge, this is the first case of rheumatoid nodules involving the larynx with voice change in Korea.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Case of Rheumatoid Nodules Involving the Larynx

Seo¹,

Choi²,

Bang³

et al. 2019

Korean J Otorhinolaryngol-Head Neck Surg

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A Case of Rheumatoid Nodules Involving the Larynx

Seo¹,

Choi²,

Bang³

et al. 2019

Korean J Otorhinolaryngol-Head Neck Surg

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“…Less commonly we can see crico-arytenoid subluxation (39.9%), decrease in the cricoarytenoid joint space, erosion and ankylosis of the cricoarytenoid joint, and soft tissue changes, such as narrowing around the glottis and pyriform fossae (Fig. 5) [46,47]. MRI scans can also be used [3].…”

Section: Discussionmentioning

confidence: 99%

Laryngeal Involvement in Connective Tissue Disorders. Is it Important for Patient Management?

Iacovou

Vlastarakos

Nikolopoulos³

2012

Indian J Otolaryngol Head Neck Surg

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Connective tissue disorders (CTDs) involve multiple organ systems and may have a significant impact on the overall health and quality of life of the affected individuals. The present paper aims to review the current knowledge on the laryngeal manifestations of CDTs, and describe the available diagnostic and treatment options. Systematic literature review in Medline and other database sources. Information from related books was also included. Prospective controlled, double-blind prospective, prospective, and transversal cohort studies, case series, case reports, systematic reviews, and consensus papers. Laryngeal involvement mostly occurs in rheumatoid arthritis (13-75% of patients). It is not uncommon in active and progressive clinical course, though can also occur in silent or inactive CDTs. The crico-arytenoid joint is the most commonly affected site. Common symptoms include throat pain, dyphonia and hoarseness. Careful clinical assessment of the larynx by flexible naso-endoscopy, video-stroboscopy, or direct laryngoscopy, and appropriate imaging are required for pertinent patient management. Stridor is a sign of a life-threatening condition, and may require prompt surgical intervention. However, mild symptomatology may mislead clinicians, and the related diagnosis may be significantly delayed. The current evidence as identified in the present study suggest that laryngeal manifestations of CDTs are often underdiagnosed, due to a range of nonspecific symptoms. A multidisciplinary team approach with ENT input is necessary to improve the overall patient management.

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“…Bronchiolitis obliterans, a form of severe constrictive bronchiolitis, occurs rarely in young patients with RA and constitutes an untreatable condition leading to severe respiratory failure and premature death [59] . Rarely also the upper airways may be involved in RA under different forms such as rheumatoid nodules of the vocal cords, vasa nervorum vasculitis of the recurrent laryngeal and/or vagus nerves, and cricoarytenoid arthritis [60] . Occasionally, emergency measures may become necessary to ensure the patency of the airways [61] .…”

Section: Airway Diseasementioning

confidence: 99%

Investigation of Lung Involvement in Connective Tissue Disorders

Papiris¹,

Manali²,

Kolilekas³

et al. 2015

Respiration

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Lung involvement in connective tissue disorders (CTDs) may present as pleomorphic since any lung compartment may be involved such as airways, exocrine secretory and alveolar epithelia, interstitial lung structure, pulmonary vasculature and pleura as well as, in specific disorders, several tissues of the thoracoabdominal ventilator pump. Any combination of the above anatomic structures may be involved concomitantly although some specific combinations may include a determinant of rheumatic disorders. The diagnosis of a specific CTD requires the fulfilment of clearly defined clinical and laboratory criteria including in most cases positivity for autoantibodies, mostly specific serologic combinations. In this setting, serologic investigation targets mainly, although not exclusively, the detection of antinuclear antibodies. A specific serologic positivity or a combination of autoantibodies constitutes not only a diagnostic criterion for a specific CTD, but may also characterize the pattern of respiratory manifestation in a determinant rheumatic disorder. Therefore, the investigation of lung involvement in CTDs requires adequate skills in the ambit of a multidisciplinary approach and an extended spectrum of diagnostic tools and modalities able to detect both early clinical clues and serologic conversion as well as any pathophysiologic alteration that regards the complexity of respiratory functional status. Although many patients with CTDs suffer from a ‘vicious' combination of lung involvement, lung drug toxicity and infections related to the above two as well as to the ‘mater' disease, for space reasons this review will focus on the established lung manifestations that regard the 7 major CTDs.

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Laryngeal Manifestations of Rheumatoid Arthritis

Cited by 38 publications

References 43 publications

A Case of Rheumatoid Nodules Involving the Larynx

A Case of Rheumatoid Nodules Involving the Larynx

Laryngeal Involvement in Connective Tissue Disorders. Is it Important for Patient Management?

Investigation of Lung Involvement in Connective Tissue Disorders

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