Laryngeal tuberculosis: A report of 17 cases

Kurokawa, Masashi; Nibu, Ken‐ichi; Ichimura, Keiichi; Nishino, Hiroshi

doi:10.1016/j.anl.2015.02.012

Cited by 40 publications

(28 citation statements)

References 18 publications

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“…Some scholars 13 reported that smoking is the risk factor associated with the LTB 13,14 ; 64.7% of patients had a history of smoking in this study. Kurokawa et al 14 showed that 52.9% of patients with LTB had a history of smoking. In addition, most of the patients with LTB had systemic symptoms such as a cough, fever, weight loss, and night sweats in the past, 3,6,9,14-16 and only 2 (11.8%) patients had systemic symptoms in this study.…”

Section: Discussionmentioning

confidence: 55%

Leukoplakia or LPR: The Misdiagnosis of Laryngeal Tuberculosis

Lou¹,

2019

Ear Nose Throat J

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Objective:The objective is to reduce the rates of misdiagnosis and inappropriate treatment of laryngeal tuberculosis (LTB).Study Design:Retrospective case series.Materials and Methods:Medical records of 3 histopathology-confirmed cases at a tertiary medical center from 2000 to 2018.Results:Seventeen patients with LTB included in this study. Of the 17 patients, 16 patients were male and 1 was female; 11 patients had a history of smoking. Odynophagia was the chief complaint in 6 cases, and 11 patients complained of hoarseness. The appearance of the affected larynx was ranged from diffuse swelling (n = 7, 41.2%), mucosa white lesion (n = 5,29.4%), and granulomatous tumors (n = 2, 11.76%), and these features presented together (n = 2, 11.76%). Seventeen patients with LTB were misdiagnosed as acute epiglottitis in 4 (23.5%) patients, acute laryngitis in 1 (5.9%) patient, leukoplakia in 5 (29.4%) patients, laryngopharyngeal reflux (LPR) in 6 (35.3%) patients, and laryngocarcinoma in 1 (5.9%) patient. Chest computed tomography reported old pulmonary tuberculosis in 2 (11.7%) patients, active pulmonary tuberculosis in 7 (41.2%) patients, and normal lung status in 8 (47.1%) patients. Histopathological examination reported Mycobacterium tuberculosis infection by revealing epithelioid cell granulomas with Langhans-type giant cells in 14 (82.4%) patients and epithelioid cell granulomas with caseous necrosis and Langhans-type giant cells in 3 (17.6%) patients.Conclusions:Laryngeal tuberculosis was easily misdiagnosed as acute epiglottitis or leukoplakia because of diffuse swelling of the epiglottis or white lesions over the true vocal cord, especially patients with increasing LTB were misdiagnosed as LPR with the enhancement of LPR awareness among otolaryngologist. Clinicians should be aware of the possibility of LTB for chronic intractable laryngitis with failure treatment of proton pump inhibitor and recurrent acute epiglottitis with foreign body injury.

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Section: Discussionmentioning

confidence: 55%

Leukoplakia or LPR: The Misdiagnosis of Laryngeal Tuberculosis

Lou¹,

2019

Ear Nose Throat J

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“…Tuberculosis laryngitis is a well‐known entity and can cause hoarseness due to direct vocal cord involvement. Laryngeal involvement occurs by direct inoculation of the vocal cords . The possibility of tuberculous laryngitis was of concern in this patient due residing in countries with a high prevalence of tuberculosis.…”

Section: Discussionmentioning

confidence: 87%

Chronic laryngitis caused by Mycobacterium Kansasii in a traveler

et al. 2019

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Chronic laryngitis commonly presents with dysphonia, and infectious causes include tuberculosis and endemic mycoses. We present a 58-year-old female with laryngitis for 5 years, fevers, chills, fatigue, malaise, myalgias, anterior neck pain, and night sweats after multicontinent exposure. Bronchoscopy cultures were negative. Bilateral microflap excision of vocal fold lesions demonstrated thickened epithelium and a deep vocal fold mass. Biopsy showed necrotizing granulomatous inflammation with acid-fast bacilli. Mycobacterium kansasii was identified. Treatment led to improvement in dysphonia, systemic symptoms, and vocal fold irritation. To our knowledge, this is the first case of isolated nontuberculous mycobacterial vocal fold infection.

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“…Masashi reported 17 cases of laryngeal TB obtained 94.1% of patients with lung abnormalities in the picture on a chest X-ray images and 5.9% with normal lung. 9 Chen reported 26 cases of laryngeal TB with a picture of abnormalities in the lungs by 92.3% and 7.2% without abnormalities image. 10 Examinations abnormalities in chest X-ray and complete blood count is done to evaluate the possible involvement of pulmonary tuberculosis infection.…”

Section: Discussionmentioning

confidence: 99%

Primary laryngeal tuberculosis

Brahmono

Purnami

Yusuf

2019

Int J Otorhinolaryngol Head Neck Surg

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In addition, on the physical examination there were obtained no abnormality. While, on fiber optic ABSTRACT Primary laryngeal tuberculosis (TB) is a very rare disease that became the most common causes of granuloma disease in the larynx. The manifestasion of tuberculosis on the laryngeal is commonly local without systemic symptom. This case reported was 21 year old male that complained of hoarseness for 6 months. The results of the fiber optic laryngoscopy (FOL) is generally believed a papilloma of the larynx. Biopsy extraction with microlaryngeal surgery was a mandatory procedure that apparently showing an overview of TB based on the results of histopathology and polymerase chain reaction (PCR). Anti-tuberculosis drugs were given to the patients, the evaluation carried out six months after the patient obtain intensive therapy and continue therapy with good result. Due to the non spesific laryngeal sign that was observed on clinical examination, clinicians must consider the possibility of primary laryngeal tuberculosis. Biopsy the lession on larynx continued with histopathology examination must not hesitate to confirm the diagnosis. PCR can be considered the better way to detect the TB bacteria.

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Laryngeal tuberculosis: A report of 17 cases

Cited by 40 publications

References 18 publications

Leukoplakia or LPR: The Misdiagnosis of Laryngeal Tuberculosis

Leukoplakia or LPR: The Misdiagnosis of Laryngeal Tuberculosis

Chronic laryngitis caused by Mycobacterium Kansasii in a traveler

Primary laryngeal tuberculosis

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