Laryngotracheal-esophageal cleft

Geiger, James P.; O'Connell, Thomas J.; Carter, Samuel C.; Gomez, Alphonse C.; Aronstam, Elmore M.

doi:10.1016/s0022-5223(19)42466-5

Cited by 16 publications

(4 citation statements)

References 5 publications

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“…Laryngeal cleft is a commonly reported comorbidity, likely because laryngeal cleft and EA/TEF have similar embryonic origins. However, much of the literature regarding the association between these 2 conditions is in the form of case reports or small case series . To our knowledge, the present study includes the largest number of patients with both EA/TEF and laryngeal cleft reported in the literature to date.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of Laryngeal Cleft in Pediatric Patients With Esophageal Atresia

Londahl

Irace

Kawai

et al. 2018

JAMA Otolaryngol Head Neck Surg

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Section: Discussionmentioning

confidence: 99%

“…However, much of the literature regarding the association between these 2 conditions is in the form of case reports or small case series. 2,[14][15][16][17][18][19][20][21] To our knowledge, the present study includes the largest number of patients with both EA/TEF and laryngeal cleft reported in the literature to date.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Laryngeal Cleft in Pediatric Patients With Esophageal Atresia

Londahl

Irace

Kawai

et al. 2018

JAMA Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

“…9 Early diagnosis and surgical repair of this defect is important to reduce pulmonary injury occurring as a consequence of repeated aspiration. 10,11 The primary goal of treatment is to minimize respiratory complications related to aspiration and to resolve feeding difficulties. 10 Most cases of LC are sporadic, but some patients can have associated anomalies such as TEF with or without EA.…”

Section: Discussionmentioning

confidence: 99%

“…10,11 The primary goal of treatment is to minimize respiratory complications related to aspiration and to resolve feeding difficulties. 10 Most cases of LC are sporadic, but some patients can have associated anomalies such as TEF with or without EA. The incidence of this particular association is difficult to assess because most of the literature regarding this association is in the form of case reports or small series.…”

Section: Discussionmentioning

confidence: 99%

The association between laryngeal cleft and tracheoesophageal fistula: Myth or reality?

et al. 2014

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Objectives/Hypothesis: Laryngeal cleft (LC) associated with tracheoesophageal fistula (TEF) with or without esophageal atresia (EA) has rarely been described. The purpose of this study is to review our experience, clinical features, management, delay in diagnosis, and complications in children with these anomalies.Study Design: Retrospective chart review at pediatric tertiary referral center. Methods: Patients diagnosed with LC alone or LC and TEF over a 10-year period were included. Data including demographics, type of TEF and LC, comorbidities, symptoms, management, complications and swallowing outcomes were analyzed.Results: There were 161 pediatric patients diagnosed with LC alone and 22 with LC and TEF. In patients with LC and TEF, aspiration was the most common presenting symptom (n 5 11, 50%). Seventeen patients (77%, mean age 4 years 7 months) underwent endoscopic repair and five patients (23%) with type I clefts did not require surgery. Two patients required revision surgery. For patients with LC alone, the mean age at repair was 3.70 years (4 months-19.9 years) compared to 4.69 years (8 months-17.83 years) for patients with LC and TEF (P 5 0.0187). The postoperative swallowing studies from 15 patients showed no aspiration. Mean follow-up was 4 years and 6 months.Conclusion: The diagnosis and management of LC in patients with TEF is often delayed. If a child presents with persistent aspiration after TEF repair, a complete airway endoscopy should be performed to evaluate for vocal fold mobility and cleft. Endoscopic repair is the recommended approach for those patients requiring surgical intervention.

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Laryngeal cleft: Report of eight patients and a review of the literature

1985

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Eight cases of laryngeal cleft are presented and the literature on this topic is reviewed. Patients most frequently present with stridor, respiratory distress, or a history of choking while feeding. A number of cases are found at autopsy or surgery. Laryngeal cleft frequently is found associated nonspecifically with tracheoesophageal fistula, cleft lip and cleft palate, and congenital heart defects. Laryngeal cleft may be a component manifestation of several syndromes, eg, the G syndrome, and the Pallister-Hall syndrome of congenital hypothalamic hamartoblastoma, hypopituitarism, imperforate anus, and postaxial polydactyly. Surgical treatment is successful in more than 50% of the reported cases, depending on the extent of the cleft. Cleft larynx is most likely a developmental field defect, occurring coincidentally with separation of larynx and esophagus and closure of the larynx.

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Laryngotracheal-esophageal cleft

Cited by 16 publications

References 5 publications

Prevalence of Laryngeal Cleft in Pediatric Patients With Esophageal Atresia

Prevalence of Laryngeal Cleft in Pediatric Patients With Esophageal Atresia

The association between laryngeal cleft and tracheoesophageal fistula: Myth or reality?

Laryngeal cleft: Report of eight patients and a review of the literature

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