Objective: To investigate the clinical value, technique, indications and contraindications of laryngotracheal closure (LTC) and cricopharyngeal myotomy (CPM) for intractable aspiration and dysphagia secondary to a cerebrovascular accident (CVA). Materials and Methods: Patients (n = 45) with intractable aspiration and dysphagia secondary to a CVA were treated with LTC and CPM. The LTC was performed by suturing the double cords, and packing the strap muscle flap into the subglottic tracheal cavity. Results: Intractable aspiration was completely eradicated in all patients. The swallowing function was partially improved, and the patients’ quality of life was greatly improved. It became easier to care for these patients after surgery. Conclusions: LTC and CPM are suitable for intractable aspiration and dysphagia secondary to a CVA.