Laryngotracheoesophageal Cleft; Neonatal Presentation and Diagnostic Challenges

Alnemri, Abdul Rahman; Ibraheem, Ashraf H.; Alqahtani, Yahia; Alshahrani, Safar M.

doi:10.1016/s1658-3612(10)70124-4

Cited by 2 publications

(2 citation statements)

References 10 publications

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“…In which phase the fusion process interruption occurs, determine the length of cleft [3] , [7] . Males are affected more than females [1] , [8] , but in the index case, we report a female in contrast to most of the earlier reported cases. Contributing conditions such as prematurity and polyhydramnios have been reported in the majority of previous cases [8] , but surprisingly our case was born at term without a prenatal history of polyhydramnios.…”

Section: Discussioncontrasting

confidence: 82%

Laryngotracheoesophageal Cleft Type 3 and Severe Laryngotracheomalacia; Delayed Surgical Repair, a Treatment Challenge with an Excellent Outcome

Khaleghnejad

Sadr

Tabatabaei

et al. 2018

Respiratory Medicine Case Reports

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Laryngotracheoesophageal clefts (LTEC) are rare malformations which involve the upper respiratory and digestive tract. Surgical repair should be undertaken promptly to maintain a secure airway and prevent serious pulmonary aspiration. This paper reports the first case of LTEC type 3 with severe laryngotracheomalacia that was brought to Mofid children's hospital in late infancy with a poor health status. Delayed defect correction was our team strategy for the patient when she had achieved good weight gain. At the age of 22 months in collaboration with the pediatric surgical and otolaryngologist team, the repair of the laryngeal cleft was done with lateral open approach method. She was discharged with tracheostomy and gastrostomy. In the next six months follow up after the surgery tracheostomy decannulation and gastrostomy tube removal were done and the infant is now in regular follow-up.

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Section: Discussioncontrasting

confidence: 82%

Laryngotracheoesophageal Cleft Type 3 and Severe Laryngotracheomalacia; Delayed Surgical Repair, a Treatment Challenge with an Excellent Outcome

Khaleghnejad

Sadr

Tabatabaei

et al. 2018

Respiratory Medicine Case Reports

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“…No specific pathognomonic prenatal findings associated with laryngeal clefts exist. The polyhydramnios, observed in the index patient, is a very common finding described in many cases of airway clefts (Carr et al, 1999;Alnemri et al, 2010;Seidl et al, 2021), and is attributed to impaired fetal swallowing. Absent stomach bubble, as reported in our case, is also a prenatal fetal finding in LTCs.…”

Section: Discussionmentioning

confidence: 97%

Laryngotracheoesophageal Cleft Type IV in a Preterm Neonate. A Case Report and Literature Review

Sokou,

Batsiou,

Konstantinidi

et al. 2024

Prague Med. Rep.

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We present a case of a preterm neonate with a type IV laryngo-tracheo-oesophageal cleft, an uncommon congenital malformation, resulting from the failure of separation of the trachea and the oesophagus during fetal development, often associated with other deformities as well. Data in the literature shows that the long-term morbidity from the entity has declined over the last decades, even though prognosis remains unfavourable for types III and IV. This report emphasizes the complex issues neonatologists are faced with, when treating neonates with this rare disorder in the first days of life, what will raise suspicion of this rare medical entity, and that direct laryngoscopy/bronchoscopy finally depicts the exact extension of the medical condition. At the same time extensive evaluation for coexisting congenital anomalies should be performed. For all the above reasons, these neonates should be treated in specialized tertiary pediatric centers for multidisciplinary prompt management, which may improve, the outcome.

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Laryngotracheoesophageal Cleft; Neonatal Presentation and Diagnostic Challenges

Cited by 2 publications

References 10 publications

Laryngotracheoesophageal Cleft Type 3 and Severe Laryngotracheomalacia; Delayed Surgical Repair, a Treatment Challenge with an Excellent Outcome

Laryngotracheoesophageal Cleft Type 3 and Severe Laryngotracheomalacia; Delayed Surgical Repair, a Treatment Challenge with an Excellent Outcome

Laryngotracheoesophageal Cleft Type IV in a Preterm Neonate. A Case Report and Literature Review

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