Laser Ablation for Prostate Cancer Therapies: Mathematical Modeling

Andreozzi, Assunta; Iasiello, Marcello; Napoli, Giovanni; Vanoli, Giuseppe Peter

doi:10.1615/ichmt.2024.cht-24.160

Proceeding of Proceedings of the 9th CHT-24 ICHMT International Symposium on Advances in Computational Heat Transfer May 26 - 3 2024

DOI: 10.1615/ichmt.2024.cht-24.160

|View full text |Cite

Laser Ablation for Prostate Cancer Therapies: Mathematical Modeling

Assunta Andreozzi,

Marcello Iasiello,

Giovanni Napoli

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2025

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Fluid Flow and Thermal Analysis of Blood Flow in an Automatically Generated 2d Vascular Network Featuring the Porous Media-Based Outflow Boundary Conditions

Adabbo,

Andreozzi,

Iasiello

et al. 2025

Comput Thermal Scien

View full text Add to dashboard Cite

Blood flow and thermal analyses in biological tissues are utterly important to better understand the transport phenomena in human tissues with reference to cardiovascular diseases, drug delivery, and thermal ablation. In the existing literature, there is room for new computationally lighter numerical analyses, including both fluid flow and heat transfer. This paper presents an analysis of blood thermo-fluid dynamics within an automatically generated two-dimensional (2D) vascular network, employing the constrained constructive optimization algorithm for structure generation, the porous media assumption for outflow boundary conditions, and heat transfer coefficient analysis for terminal vessels. Through comparisons with theoretical results, the model demonstrates mathematical robustness. Results of the simulations show that blood velocity decreases with increasing number of bifurcations, offering quantitative insights into its decay in magnitude and on its impact on heat transfer. Blood temperature rises in vessels with low velocity, hindering its cooling effects in the surrounding tissues. The study highlights the influence of bifurcation levels on heat transfer coefficient reduction, suggesting longer pathways and time periods to reach high temperature within the blood vessels, due to the cooling effect of pulsating blood flow in larger vessels. The quantitative analysis of the heat transfer coefficient and Nusselt number provides insights into heat transfer between blood and the surrounding tissue, offering also valuable information for numerical bioheat models in thermal therapy simulations.

show abstract

Fluid Flow and Thermal Analysis of Blood Flow in an Automatically Generated 2d Vascular Network Featuring the Porous Media-Based Outflow Boundary Conditions

Adabbo,

Andreozzi,

Iasiello

et al. 2025

Comput Thermal Scien

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Laser Ablation for Prostate Cancer Therapies: Mathematical Modeling

Cited by 1 publication

References 22 publications

Fluid Flow and Thermal Analysis of Blood Flow in an Automatically Generated 2d Vascular Network Featuring the Porous Media-Based Outflow Boundary Conditions

Fluid Flow and Thermal Analysis of Blood Flow in an Automatically Generated 2d Vascular Network Featuring the Porous Media-Based Outflow Boundary Conditions

Contact Info

Product

Resources

About