Laser ablation methods for analysis of urinary calculi: Comparison study based on calibration pellets

A standard sample preparation and calibration procedure for imaging zinc and magnesium in rats' brain tissue by laser ablation-inductively coupled plasma-time of flight-mass spectrometry

“…For the LA-ICP-MS calibration different strategies are applicable depending on the type of sample, but for imaging it is very popular to base this on a matrix-matched standard. 4,[17][18][19] Applied modication of standard sample preparation like (a) spiking with a non-acidied standard solution obtained by the dissolving of adequate solid salt; (b) reducing the number of analytes spiked into a standard sample and thus the added volume and (c) immediately freezing the homogenized standard with liquid nitrogen, signicantly improved the general appearance of standards. Moreover the obtained standards look homogenous with respect to analyte distribution.…”

Traditional Calibration Methods in Atomic Spectrometry and New Calibration Strategies for Inductively Coupled Plasma Mass Spectrometry

“…As an example of a non-successful application of this strategy, Štěpánková et al ( 2013 ) evaluated the use of Ca as IS for the analysis of urinary calculi by LIBS. According to the authors, Ca concentrations were not homogeneous throughout the samples due to the different crystalline phases, which compromised the efficiency of the IS method.…”

Sample treatment and preparation for laser-induced breakdown spectroscopy

“…One point that should be emphasized concerns the preparation protocol, which must be free of any contamination, especially since the elements of interest are in most cases rather common mineral elements, such as Ca, Na, Mg or K. The preparation of biological specimens is often very similar to solid or liquid preparation methods. For example, many studies used pellets (see Section 3.3.1), mostly for dried plants and vegetables [30,42,[93][94][95][96][97][98][99], but also for animal tissue [100][101][102], bacteria [103,104], urinary calculi [105] and milk [106]. This protocol is by far the most commonly used for quantitative biological analysis, since it also allows calibration samples to be prepared relatively easily [30,33,107].…”