“…Furthermore, the insertion of a biliary stent does not relieve biliary obstruction due to the viscous nature of the mucus. The use of cholangioscopy-guided laser to dissect benign biliopancreatic ductal strictures [2,3] and for ablation of cholangiocarcinoma [4] has been reported previously. Our experience suggests that laser has good ablative effects and may be a promising treatment modality for IPNB, particularly for patients who are unfit for surgery.…”