Laser additive manufacturing of magnesium alloys and its biomedical applications

Liu, Chuyi; Ling, Chengrong; Chen, Cheng; Wang, Dongsheng; Yang, Youwen; Xie, Dexin; Shuai, Cijun

doi:10.18063/msam.v1i4.24

Cited by 7 publications

(2 citation statements)

References 67 publications

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“…Powder bed fusion is an additive manufacturing technique, which has enabled the fabrication of geometrically complex metallic structures. 1,2 The basis of this technology is the selective consolidation of thin layers of metallic powders via processing with a focused high energy laser beam based on a computer aided design model. Among these technologies, selective laser melting (SLM) is arguably more suited to small feature resolution.…”

Section: Introductionmentioning

confidence: 99%

Chemical etching of Ti‐6Al‐4V biomaterials fabricated by selective laser melting enhances mesenchymal stromal cell mineralization

O'Keeffe,

Kotlarz,

Gonçalves

et al. 2024

J Biomedical Materials Res

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Porous titanium scaffolds fabricated by powder bed fusion additive manufacturing techniques have been widely adopted for orthopedic and bone tissue engineering applications. Despite the many advantages of this approach, topological defects inherited from the fabrication process are well understood to negatively affect mechanical properties and pose a high risk if dislodged after implantation. Consequently, there is a need for further post‐process surface cleaning. Traditional techniques such as grinding or polishing are not suited to lattice structures, due to lack of a line of sight to internal features. Chemical etching is a promising alternative; however, it remains unclear if changes to surface properties associated with such protocols will influence how cells respond to the material surface. In this study, we explored the response of bone marrow derived mesenchymal stem/stromal cells (MSCs) to Ti‐6Al‐4V whose surface was exposed to different durations of chemical etching. Cell morphology was influenced by local topological features inherited from the SLM fabrication process. On the as‐built surface, topological nonhomogeneities such as partially adhered powder drove a stretched anisotropic cellular morphology, with large areas of the cell suspended across the nonhomogeneous powder interface. As the etching process was continued, surface defects were gradually removed, and cell morphology appeared more isotropic and was suggestive of MSC differentiation along an osteoblastic‐lineage. This was accompanied by more extensive mineralization, indicative of progression along an osteogenic pathway. These findings point to the benefit of post‐process chemical etching of additively manufactured Ti‐6Al‐4V biomaterials targeting orthopedic applications.

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Section: Introductionmentioning

confidence: 99%

Chemical etching of Ti‐6Al‐4V biomaterials fabricated by selective laser melting enhances mesenchymal stromal cell mineralization

O'Keeffe,

Kotlarz,

Gonçalves

et al. 2024

J Biomedical Materials Res

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show abstract

“…At the same time, AM is environment friendly as it primarily uses recyclable materials and reduces waste 24 . The versatility of AM technology has made it an effective and powerful tool for preparing complex and delicate structures, especially those considered challenging to fabricate by conventional means 14,19,25–29 …”

Section: Introductionmentioning

confidence: 99%

Droplet interface in additive manufacturing: From process to application

Sun

Deng

et al. 2023

Droplet

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Additive manufacturing (AM), which is often referred to as three-dimensional printing, revolutionizes manufacturing by providing a high degree of design freedom and customization. Several AM methods entail precise control of droplet interfacial properties to ensure the high quality of the printed products. At the same time, the rapid growth of AM technology has made it possible to prepare novel surfaces with complex structures, further expanding the range of potential applications of droplet interface. To provide a unified framework to guide the continuous development of

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The effect of TiC addition on the mechanical properties and thermal expansion coefficient during laser metal deposition of invar 36 alloy

Li,

Guan,

Liu

et al. 2025

Engineering Failure Analysis

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Laser additive manufacturing of magnesium alloys and its biomedical applications

Cited by 7 publications

References 67 publications

Chemical etching of Ti‐6Al‐4V biomaterials fabricated by selective laser melting enhances mesenchymal stromal cell mineralization

Chemical etching of Ti‐6Al‐4V biomaterials fabricated by selective laser melting enhances mesenchymal stromal cell mineralization

Droplet interface in additive manufacturing: From process to application

The effect of TiC addition on the mechanical properties and thermal expansion coefficient during laser metal deposition of invar 36 alloy

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