Laser cellulite treatment and laser‐assisted lipoplasty of the thighs and buttocks: Combined modalities for single stage contouring of the lower body

Petti, Christine; Stoneburner, Jacqueline; McLaughlin, Laura

doi:10.1002/lsm.22437

Cited by 12 publications

(9 citation statements)

References 30 publications

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“…MRI and ultrastructural results could influence the microsurgical methods proposed until now to treat the dimpling [19,20], or therapies based on radiofrequency [21] and on laser employment [22]. Most of these techniques, in fact, are based on the collagen fiber remodeling or cutting, but we are not sure that the remodeling of collagen septa is the most efficient method to treat cellulite.…”

Section: Discussionmentioning

confidence: 99%

Proteomic and Ultrastructural Analysis of Cellulite—New Findings on an Old Topic

Conti

Zingaretti

Amuso

et al. 2020

IJMS

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Background: Cellulite is a condition in which the skin has a dimpled lumpy appearance. The main causes of cellulite development, studied until now, comprehends modified sensitivity to estrogens, the damage of microvasculature present among dermis and hypodermis. The differences of adipose tissue architecture between male and female might make female more susceptible to cellulite. Adipose tissue is seen to be deeply modified during cellulite development. Our study tried to understand the overall features within and surrounding cellulite to apply the best therapeutic approach. Methods: Samples of gluteal femoral area were collected from cadavers and women who had undergone surgical treatment to remove orange peel characteristics on the skin. Samples from cadavers were employed for an accurate study of cellulite using magnetic resonance imaging at 7 Tesla and for light microscopy. Specimens from patients were employed for the proteomic analysis, which was performed using high resolution mass spectroscopy (MS). Stromal vascular fraction (SVF) was obtained from the samples, which was studied using MS and flow cytometry. Results: light and electron microscopy of the cellulite affected area showed a morphology completely different from the other usual adipose depots. In cellulite affected tissues, sweat glands associated with adipocytes were found. In particular, there were vesicles in the extracellular matrix, indicating a crosstalk between the two different components. Proteomic analysis showed that adipose tissue affected by cellulite is characterized by high degree of oxidative stress and by remodeling phenomena. Conclusions: The novel aspects of this study are the peculiar morphology of adipose tissue affected by cellulite, which could influence the surgical procedures finalized to the reduction of dimpling, based on the collagen fibers cutting. The second novel aspect is the role played by the mesenchymal stem cells isolated from stromal vascular fraction of adipose tissue affected by cellulite.

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Section: Discussionmentioning

confidence: 99%

Proteomic and Ultrastructural Analysis of Cellulite—New Findings on an Old Topic

Conti

Zingaretti

Amuso

et al. 2020

IJMS

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“…The appearance of skin laxity and cellulite can negatively affect an individual’s quality of life. Numerous therapeutic approaches with varying degrees of effectiveness have been described, including topical products, 12 , 13 radiofrequency, 14 – 16 laser therapy, 17 – 19 and carboxytherapy. 20…”

Section: Introductionmentioning

confidence: 99%

Microfocused Ultrasound with Visualization and Calcium Hydroxylapatite for Improving Skin Laxity and Cellulite Appearance

Casabona

Pereira

2017

Plastic and Reconstructive Surgery - Global Open

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Background:Age-associated skin laxity contributes to worsening of cellulite appearance. This study evaluated the effects of microfocused ultrasound with visualization (MFU-V; Ultherapy) in combination with diluted calcium hydroxylapatite (CaHA; Radiesse) on cellulite appearance and on neocollagenesis.Methods:Twenty women (18–55 years old) with skin laxity and moderate-to-severe cellulite on the buttocks and thighs were retrospectively enrolled. MFU-V was applied using 4 and 7 MHz transducers (25 lines/transducer/site) and immediately followed by subdermal CaHA injection (1 ml/buttock or thigh). Photographs at baseline and 90 days were assessed by 2 independent, blinded evaluators using a 5-item cellulite severity scale. One subject scheduled for thighplasty received treatment with 6 different CaHA dilutions (0.3 ml/5 cm2) followed by MFU-V. Tissue specimens from each dilution site were examined under polarized light microscopy to assess neocollagenesis.Results:Both evaluators reported statistically significant improvements compared with baseline for each item on the cellulite severity scale (P < 0.001) with a 4.5-point improvement in mean overall score (P < 0.001) after a single MFU-V/CaHA treatment. At 90 days, histologic analysis showed peak neocollagenesis in samples treated with the 1:1 dilution, whether with CaHA alone or in combination with MFU-V. The highest conversion of collagen type III into collagen type I at month 3 occurred in samples injected with 1:1 and 1:0.6 CaHA dilutions without subsequent MFU-V treatment. Both procedures were well tolerated, and subject satisfaction was high.Conclusions:Combination treatment with MFU-V and diluted CaHA is effective for improving skin laxity and the appearance of cellulite on the buttocks and upper thighs.

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“…An average improvement score was 1.58 on a scale from 1 to 3 suggesting significant satisfaction rate on the final esthetic appearance. [26] The authors have used laser-assisted lipolysis to treat skinny patient with localized cellulite with high satisfaction rate.…”

Section: Discussionmentioning

confidence: 99%

Laser-Assisted Liposuction in Face and Body Contouring

Žgaljardić¹,

Žgaljardić²

2022

Enhanced Liposuction - New Perspectives and Techniques

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Laser liposuction was developed as minimally invasive liposuction technique where energy breaks adipocytes (comparing with traditional liposuction where disruption is manual). After its implementation in the early 1990s, various academic reports were published that showed superiority of the laser assisted liposuction over standard tumescent technique. After tissue damage with photo-optical thermal energy, histological changes result in adipocyte disruption, blood vessel coagulation and neocollagenesis. The clinical manifestation of the latter is significant skin tightening and faster and more comfortable recovery. The diameter of the laser fiber is very small. Therefore, it is possible to reach adipose tissue entrapped in fibrotic areas and also superficially under the skin. The lysis of the given adipose tissue enables the subsequent suction with microcannulas. That explains the widespread use of the laser-assisted liposuction in the face and neck. Due to the significant skin tightening, the procedure can be done solely for rejuvenation purposes and is called endolight lifting. The possibility to reach fat in the fibrotic areas makes laser-assisted lipolysis/liposuction ideal procedure for contouring irregularities from previous body contouring procedures.

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Laser cellulite treatment and laser‐assisted lipoplasty of the thighs and buttocks: Combined modalities for single stage contouring of the lower body

Abstract: Precise, effective delivery of laser energy to the dermal-adipose tissue, as well as the deep adipose lipodystrophy is feasible as a safe modality for the simultaneous treatment of cellulite and lipodystrophy in the buttocks and thighs, as a single stage procedure.

Cited by 12 publications

References 30 publications

Proteomic and Ultrastructural Analysis of Cellulite—New Findings on an Old Topic

Proteomic and Ultrastructural Analysis of Cellulite—New Findings on an Old Topic

Microfocused Ultrasound with Visualization and Calcium Hydroxylapatite for Improving Skin Laxity and Cellulite Appearance

Laser-Assisted Liposuction in Face and Body Contouring

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