Laser Doppler Anemometer Studies in Unsteady Ventricular Flows

Wm, Phillips; Ss, Furkay; Ws, Pierce

doi:10.1097/00002480-197902500-00011

Cited by 15 publications

(2 citation statements)

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“…Early fluid mechanics studies were through flow visualization (Lenker 1978, Phillips et al 1972, single-component laser Doppler anemometry (Phillips et al 1979), hot film anemometry in conjunction with dye washout (Affeld 1979), and pulsed Doppler ultrasound (Mann et al 1987, Tarbell et al 1986). Flow visualization continues to be useful for qualitative assessment.…”

Section: Early Experiments In Briefmentioning

confidence: 99%

Experimental Fluid Mechanics of Pulsatile Artificial Blood Pumps

Deutsch

Tarbell

Manning³

et al. 2006

Annu. Rev. Fluid Mech.

101

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The fluid mechanics of artificial blood pumps has been studied since the early 1970s in an attempt to understand and mitigate hemolysis and thrombus formation by the device. Pulsatile pumps are characterized by inlet jets that set up a rotational "washing" pattern during filling. Strong regurgitant jets through the closed artificial heart valves have Reynolds stresses on the order of 10,000 dynes/cm 2 and are the most likely cause of red blood cell damage and platelet activation. Although the flow in the pump chamber appears benign, low wall shear stresses throughout the pump cycle can lead to thrombus formation at the wall of the smaller pumps (10-50 cc). The local fluid mechanics is critical. There is a need to rapidly measure or calculate the wall shear stress throughout the device so that the results may be easily incorporated into the design process. 65 Annu. Rev. Fluid Mech. 2006.38:65-86. Downloaded from www.annualreviews.org Access provided by University of California -San Diego on 02/04/15. For personal use only.

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Section: Early Experiments In Briefmentioning

confidence: 99%

Experimental Fluid Mechanics of Pulsatile Artificial Blood Pumps

Deutsch

Tarbell

Manning³

et al. 2006

Annu. Rev. Fluid Mech.

101

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“…Such data could provide important information that may be useful in the design of these devices in order to reduce the likelihood of turbulence and/or stagnation that could lead to the activation of blood elements and a subsequent clot or thrombus formation. Although much technology exists for evaluating shear stress and blood flow velocity, the methods used are either invasive or require a translucent housing for optimum assessment (1)(2)(3)(4)(5). Hot film anemometry requires the placement of probes in the ffuid path, which creates the potential for cavitation or turbulent flow at the probe sight.…”

mentioning

confidence: 99%

Evaluating the Flow Characteristics of Artificial Pumping Devices Using Nuclear Scintigraphsy

et al. 1993

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The design and development of artificial blood pumps require qualitative and quantitative data relative to pump filling, ejection, and wall motion in order to optimize the design and maximize the pattern of blood flow through the pump. To assist in the development of an artificial heart, we utilized radionuclide scintigraphy and a high‐resolution gamma camera to evaluate the flow patterns through the pump. We performed a comparative analysis of the flow patterns in a pneumatically driven ventricular assist device (Sarns/3M VAD) and the electrically driven Milwaukee Heart. These analyses disclose some significant differences between the two devices with regard to the blood sac compression patterns and ejection as well as valvular regurgitation. On the basis of these findings, nuclear scintigraphy for analyzing fluid shear stress and flow dynamics seems a useful technique for evaluating blood flow through artificial blood pumps. Because the procedure does not require a translucent casing or direct contact with the device being studied, it would be especially useful in evaluating artificial blood pumps implanted in patients with heart failure.

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Engineering studies of the Penn State artificial heart

Geselowitz

1988

Artificial Heart 2

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Laser Doppler Anemometer Studies in Unsteady Ventricular Flows

Cited by 15 publications

References 0 publications

Experimental Fluid Mechanics of Pulsatile Artificial Blood Pumps

Experimental Fluid Mechanics of Pulsatile Artificial Blood Pumps

Evaluating the Flow Characteristics of Artificial Pumping Devices Using Nuclear Scintigraphsy

Engineering studies of the Penn State artificial heart

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