Laser doppler flowmetry assessment of microcirculation in children of 6–7 years old

Abstract

Introduction. The state of the blood flow within the capillaries and close blood vessels is highly important in practice for the revealing of pathogenetic mechanisms of both systemic and local circulatory disorders. Aim of the study was to define the parameters of microcirculation and the level of blood flow fluctuations (flux) in the distal segments of upper and lower limbs (in fingers of hands and toes of feet) in children of 6–7 years old; and to describe the possible differences in the mechanisms of blood flow modulation in boys and girls. Materials and methods. Skin microcirculation was assessed in middle fingers of hands and great toes of feet in children of 6-7 years old (14 girls and 7 boys in prone position) by means of laser doppler flowmetry. Results. The ranges for parameters of microcirculation (PM) for distal segments of upper and lower limbs in children of mentioned age group were defined, also it was shown that the PM are significantly lower in the lower limbs comparing to those of the upper limbs (both in groups of girls and boys). Asymmetry of PM in the feet was not found; the features of right hand-left hand asymmetry for PM in girls and boys are described. The analysis of modulation of blood flow fluctuations (fluxmotions) of different frequencies showed the profound role of vasomotor (myogenic) rhythm for regulation of microcirculation. Conclusion. Increased neurogenic influences on the modulation of fluxmotions in girls of 6-7 years old may be an evidence of the ongoing development of the mechanisms of blood flow regulation, particularly the association with the growth rate of girls is possible.

The Effect of Photobiostimulation by Light Waves in the Blue Range of the Spectrum on Microcirculation Parameters and the Activity of Oxidative Homeostasis Enzymes in the Skin

“…The indicator of blood microcirculation (IC) was determined by the LDF method (in the previous works on LDF, it was designated as PM). It is believed [16], that IC is determined by two factors: the concentration of red J of Biomedical Photonics & Eng 9(1) 2023 30 Mar 2023 © J-BPE 010309-4 blood cells in the probed tissue volume and their mobility (an averaged erythrocyte rate). IL is proportional to the product of the number of scatterers in the lymph flow by the average speed of their movement [11].…”

“…The frequency-amplitude analysis of LDF-grams [10,[16][17][18] defined the contribution of the vasomotion-induced physiologically most significant blood flow fluctuations within the range of 0.1 Hz and its immediate vicinity (0.07-0.15 Hz). The vasomotor biogenic rhythm is secondarily influenced by modulations of neurogenic, respiratory and cardiogenic nature that were determined by their amplitude in the corresponding frequency ranges (ANF neurogenic, AMF myogenic, AHF respiratory, and ACF cardiogenic).…”