Laser-Doppler-vibrometrische Messungen an humanen Felsenbeinen

Schraven, Sebastian P.; Dohr, Dagmar; Weiss, Nora M.; Mlynski, Robert; Dalhoff, Ernst

doi:10.1007/s00106-021-00995-5

Cited by 4 publications

(2 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Comparison between acoustic stimulation and electromechanical stimulation by an FMT has only been performed in experimental studies using Laser-Doppler vibrometry so far. These studies provided objective evidence that acoustic stimulation is mechanically different from electromechanical stimulation by the VSB (9,10). However, normative data on the characteristics of VSB evoked ABRs as a new objective method were not available in the literature so far.…”

Section: Discussionmentioning

confidence: 99%

“…With coupling location and coupling direction, which will be summarized and referred to as coupling modality here, the effective direction of stimulation varies. The output of AMEIs can be investigated by Laser-Doppler vibrometry which is also a feasible method to compare transfer functions for different coupling modalities (10). It has been shown that transfer functions for electromechanical stimulation by the FMT are different from acoustic stimulation and variations for different coupling modalities have been reported.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Active Middle Ear Implant Evoked Auditory Brainstem Response Intensity-Latency Characteristics

et al. 2022

View full text Add to dashboard Cite

ObjectiveTo analyze intensity-latency functions of intraoperative auditory evoked brainstem responses (ABRs) to stimulation by the Vibrant Soundbridge (VSB) active middle ear implant with respect to coupling efficiency, VSB evoked ABR thresholds, and coupling modality [oval window (OW) placement vs. Incus placement and vs. round window (RW) placement].Study DesignExploratory study.SettingBi-centric study at tertiary referral centers.PatientsTwenty-four patients (10 female, 14 male, mean age: 58 years) who received a VSB.Outcome MeasuresWave-V intensity-latency functions of intraoperative VSB evoked ABRs using a modified audio processor programmed to preoperative bone conduction thresholds for stimulation. Threshold level correction to coupling efficiency and ABR thresholds. Individual plots and exponential function fits.ResultsAfter ABR threshold level correction, the latency functions could be aligned. A large variance of latencies was observed at individual threshold level. Wave-V latency was longest in the Incus placement subgroup (9.73 ms, SD: 1.04) as compared to OW placement subgroup (9.47 ms, SD: 1.05), with the shortest latency in the RW placement subgroup (8.99 ms, SD: 0.68). For increasing stimulation levels, the variance decreased with intensity-latency function slopes converging toward a steady-state (saturation) latency caused by saturation of audio processor (stimulation) gain. Latency saturation was reached at a stimulation level of 50 dB nHL for the OW placement subgroup, 35 dB nHL for the Incus placement subgroup, and 30 dB nHL for the RW placement subgroup. The latency and saturation results indicated decreased dynamic range for RW placement, i.e., reverse stimulation.ConclusionsVSB evoked ABR wave-V intensity-latency function slopes were similar to acoustic stimulation at high stimulation levels with a shift toward longer latencies caused by audio processor signal delay. Saturation of latencies occurred for higher stimulation levels due to saturation of audio processor gain. Thus, the analysis of VSB evoked intensity-latency functions appears to allow for the objective assessment of a patient's individual dynamic range. This can further improve diagnostics as well as intraoperative and postoperative quality control.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Active Middle Ear Implant Evoked Auditory Brainstem Response Intensity-Latency Characteristics

et al. 2022

View full text Add to dashboard Cite

show abstract

Influence of skin flap thickness on the transmission characteristics of middle ear implant audio processors

Fröhlich,

Rahne,

Müller

et al. 2024

Zeitschrift für Medizinische Physik

View full text Add to dashboard Cite

The human middle ear in motion: 3D visualization and quantification using dynamic synchrotron-based X-ray imaging

Schmeltz,

Ivanovic,

Schlepütz

et al. 2024

Commun Biol

View full text Add to dashboard Cite

The characterization of the vibrations of the middle ear ossicles during sound transmission is a focal point in clinical research. However, the small size of the structures, their micrometer-scale movement, and the deep-seated position of the middle ear within the temporal bone make these types of measurements extremely challenging. In this work, dynamic synchrotron-based X-ray phase-contrast microtomography is used on acoustically stimulated intact human ears, allowing for the three-dimensional visualization of entire human eardrums and ossicular chains in motion. A post-gating algorithm is used to temporally resolve the fast micromotions at 128 Hz, coupled with a high-throughput pipeline to process the large tomographic datasets. Seven ex-vivo fresh-frozen human temporal bones in healthy conditions are studied, and the rigid body motions of the ossicles are quantitatively delineated. Clinically relevant regions of the ossicular chain are tracked in 3D, and the amplitudes of their displacement are computed for two acoustic stimuli.

show abstract

Laser-Doppler-vibrometrische Messungen an humanen Felsenbeinen

Cited by 4 publications

References 36 publications

Active Middle Ear Implant Evoked Auditory Brainstem Response Intensity-Latency Characteristics

Active Middle Ear Implant Evoked Auditory Brainstem Response Intensity-Latency Characteristics

Influence of skin flap thickness on the transmission characteristics of middle ear implant audio processors

The human middle ear in motion: 3D visualization and quantification using dynamic synchrotron-based X-ray imaging

Contact Info

Product

Resources

About