Water quality monitoring was an important objective in the surroundings. In this study, we investigated the sensing characteristics of the arrayed flexible chloride sensor with XBee wireless sensing system. The sensitivity and linearity of the wireless chloride sensing devices were 91.6 mV/pCl and 0.988, respectively. The hysteresis voltages were 50.14 mV and 36.71 mV during the cycles of 1 M → 10−1 M → 1 M → 10−3 M → 1 M and 1 M → 10−3 M → 1 M → 10−1 M → 1 M, respectively. The selectivity coefficients of the ClO− ion, ClO4− ion, NO3− ion and I− ion for Cl− ion were 5.0 × 10−2, 1.0 × 10−1, 5.9 × 10−3 and 5.6×10−1, respectively. The sensing characteristics of real time measurement were investigated for dynamic microfluidic. The arrayed flexible chloride sensor was integrated with the microfluidic device, syringe pump and wireless sensing system. The sensitivity and linearity were 273.1 mV/pCl and 0.978 at 35 μL/min, respectively.